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Publications 2024:
181 Barekatain M, Johansson LC, Lam JH, Chang H, Sadybekov AV, Han GW, Russo J, Bliesath J, Brice NL, Carlton MBL, Saikatendu KS, Sun H, Murphy ST, Monenschein H, Schiffer HH, Popov P, Lutomski CA, Robinson CV, Liu Z-J, Hua T, Katritch V, Cherezov V (2024) Structural insights into the high basal activity and inverse agonism of the orphan receptor GPR6 implicated in Parkinson's disease. Sci Signal 17: eado8741; PDB ID: 8T1V, 8T1W, 8TF5, 8TYW
180 Kao G, Zhang X-N, Nasertorabi F, Katz BB, Li Z, Dai Z, Zhang Z, Zhang L, Louie SG, Cherezov V, Zhang Y (2024) Nicotinamide riboside and CD38: covalent inhibition and live-cell labeling. JACS Au 4: 4345-4360; PDB ID: 8VAU
179 Chang H, Li X, Shen L, Ge X, Hao S, Wu L, Liu S, Liu J, Cherezov V, Hua T (2024) Structure basis of ligand recognition and activation of GPR55. Cell Res Published Online: 31 October 2024; PDB ID: 9IY8, 9IYA
178 Kim D, Liu W, Viner R, Cherezov V (2024) Native mass spectrometry prescreening of G protein-coupled receptor complexes for cryo-EM structure determination. Structure 32: 2206-2219.e4; PDB ID: 8VHF
177 Barekatain M, Liu Y, Archambeau A, Cherezov V, Fraser S, White KL, Hayes MA (2024) Insulator-based dielectrophoresis-assisted separation of insulin secretory vesicles. eLife 13: e74989;
176 Belousov A, Maslov I, Orekhov P, Khorn P, Kuzmichev P, Baleeva N, Motov V, Bogorodskiy A, Krasnova S, Mineev K, Zinchenko D, Zernii E, Ivanovich V, Permyakov S, Hofkens J, Hendrix J, Cherezov V, Gensch T, Baranov M, Mishin A, Borshchevskiy V (2024) Monitoring GPCR conformation with GFP-inspired dyes. iScience 27: 110466;
175 Raskovalov A, Kim D, Cherezov V (2024) One-Go: Direct detection of context-dependent GPCR activity. Cell Res 34: 543-544;

Publications 2023:
174 Luginina A, Maslov I, Khorn P, Volkov O, Khnykin A, Kuzmichev P, Shevtsov M, Belousov A, Kapranov I, Dashevskii D, Kornilov D, Bestsennaia E, Hofkens J, Hendrix J, Gensch T, Cherezov V, Ivanovich V, Mishin A, Borshchevskiy V (2023) Functional GPCR expression in eukaryotic LEXSY system. J Mol Biol 435: 168310;
173 Luginina A, Gusach A, Lyapina E, Khorn P, Safronova N, Shevtsov M, Dmitrieva D, Dashevskii D, Kotova T, Smirnova E, Borshchevskiy, Cherezov V, Mishin A (2023) Structural diversity of leukotriene G protein coupled receptors. J Biol Chem 299: 105247;
172 Zhang D, Liu Y, Zaidi SA, Xu L, Zhan Y, Chen A, Guo J, Huang X-P, Roth BL, Katritch V, Cherezov V, Zhang H (2023) Structural insights into angiotensin receptor signaling modulation by balanced and biased agonists. EMBO J : e112940; PDB ID: 7F6G
171 Lin X, Jiang S, Wu Y, Wei X, Han GW, Wu L, Liu J, Chen B, Zhang Z, Zhao S, Cherezov V, Xu F (2023) The activation mechanism and antibody binding mode for orphan GPR20. Cell Discov 9: 23; PDB ID: 8HS2, 8HS3, 8HSC
170 Maslov I, Volkov O, Khorn P, Orekhov P, Gusach A, Kuzmichev P, Gerasimov A, Luginina A, Coucke Q, Bogorodskiy A, Gordeliy V, Wanninger S, Barth A, Mishin A, Hofkens J, Cherezov V, Gensch T, Hendrix J, Borschevskiy V (2023) Sub-millisecond conformational dynamics of the A2A adenosine receptor revealed by single-molecule FRET. Commun Biol 6: 362;

Publications 2022:
169 Shiriaeva A, Park D, Kim G, Lee Y, Hou X, Jarhad DB, Kim G, Yu J, Hyun YE, Kim W, Gao Z-G, Jacobson KA, Han GW, Stevens RC, Jeong LS, Choi S, Cherezov V (2022) GPCR agonist-to-antagonist conversion: enabling the design of nucleoside functional switches for the A2A adenosine receptor. J Med Chem 65: 11648-11657; PDB ID: 8CU6, 8CU7
168 Lyapina E, Marin E, Gusach A, Orekhov P, Gerasimov A, Luginina A, Vakhrameev D, Ergasheva M, Kovaleva M, Khusainov G, Khorn P, Shevtsov M, Kovalev K, Bukhdruker S, Okhrimenko I, Popov P, Hu H, Weierstall U, Liu W, Cho Y, Gushchin I, Rogachev A, Bourenkov G, Park S, Park G, Hyun HJ, Park J, Gordeliy V, Borshchevskiy V, Mishin A, Cherezov V (2022) Structural basis for receptor selectivity and inverse agonism in S1P5 receptors. Nat Comm 13: 4736; PDB ID: 7YXA
167 Barends TRM, Stauch B, Cherezov V, Schlichting I (2022) Serial femtosecond crystallography. Nat Rev Methods Primers 2: 59;
166 Perryman R, Renziehausen A, Shaye H, Kostagianny AD, Tsiailanis AD, Thorne T, Chatziathanasiadou MV, Sivolapenko GB, El Mubarak MA, Han GW, Zazycka, Katritch V, Lebon G, Lo Nigro C, Lattanzio L, Morse SV, Choi JJ, O'Neill K, Kanaki Z, Klinakis A, Crook T, Cherezov V, Tzakos AG, Syed N. (2022) Inhibition of the angiotensin II type 2 receptor AT2R is a novel therapeutic strategy for glioblastoma. Proc Natl Acad Sci USA 119: e2116289119; PDB ID: 7JNI
165 Bolteau R, Duroux R, Laversin A, Vreulz B, Shiriaeva A, Stauch B, Han GW, Cherezov V, Renault N, Barczyk A, Ravez S, Coevoet M, Melnyk P, Liberelle M, Yous S (2022) High ligand efficiency quinazoline compounds as novel A2A adenosine receptor antagonists. Eur J Med Chem 241: 114620; PDB ID: 8DU3
164 Kovalev K, Astashkin R, Gordeliy V, Cherezov V (2022) Crystallization of microbial rhodopsins. Methods Mol Biol 2501: 125-146;
163 Motiwala Z, Aduri NG, Shaye H, Han GW, Lam JH, Katritch V, Cherezov V, Gati C (2022) Structural basis of GABA reuptake inhibition. Nature 606: 820-826; PDB ID: 7SK2

Publications 2021:
162 Martynowycz MW, Shiriaeva A, Ge X, Hattne J, Nannenga BL, Cherezov V, Gonen T (2021) MicroED structure of the human adenosine receptor determined from a single nanocrystal in LCP. Proc Natl Acad Sci USA 118: e2106041118; PDB ID: 7RM5
161 Liu H, Deepak RNVK, Shiriaeva A, Gati C, Batyuk A, Hu H, Weierstall U, Liu W, Wang L, Cherezov V, Fan H, Zhang C (2021) Molecular basis for lipid recognition by the prostaglandin D2 receptor CRTH2. Proc Natl Acad Sci USA 118: e2102813118; PDB ID: 7M8W
160 Zhang H, Luginina A, Mishin A, Baidya M, Shukla AK, Cherezov V (2021) Structural insights into ligand recognition and activation of angiotensin receptors. Trends Pharmacol Sci 42: 577-587;
159 Michaelian N, Sadybekov A, Besserer-Offroy É, Han GW, Krishnamurthy H, Zamlynny BA, Fradera X, Siliphaivanh P, Presland J, Spencer KB, Soisson SM, Popov P, Sarret P, Katritch V, Cherezov V (2021) Structural insights on ligand recognition at the human leukotriene B4 receptor 1. Nat Commun 12: 2971; PDB ID: 7K15
158 Shaye H, Stauch B, Gati C, Cherezov V (2021) Molecular mechanisms of metabotropic GABAB receptor function. Sci Adv 7: eabg3362;
157 Lemel L, Nieścierowicz K, García-Fernández MD, Darré L, Durroux T, Busnelli M, Pezet M, Rebeille F, Jouhet J, Mouillac B, Domene C, Chini B, Cherezov V, Moreau CJ (2021) The ligand-bound state of a G protein-coupled receptor stabilizes the interaction of functional cholesterol molecules. J Lipid Res 62: 100059;

Publications 2020:
156 Sadybekov AA, Brouillette RL, Marin E, Sadybekov AV, Luginina A, Gusach A, Mishin A, Besserer-Offroy É, Longpré J-M, Borshchevskiy V, Cherezov V, Sarret P, Katritch V (2020) Structure-Based Virtual Screening of Ultra-Large Library Yields Potent Antagonists for a Lipid GPCR. Biomolecules 10: 1634;
155 Marin E, Luginina A, Gusach A, Kovalev K, Bukhdruker S, Khorn P, Polovinkin V, Lyapina E, Rogachev A, Gordeliy V, Mishin A, Cherezov V, Borshchevskiy V (2020) Small-wedge synchrotron and serial XFEL datasets for Cysteinyl leukotriene GPCRs. Sci Data 7: 388;
154 Lee M-Y, Geiger J, Ishchenko A, Han GW, Barty A, White TA, Gati C, Batyuk A, Hunter MS, Aquila A, Boutet S, Weierstall U, Cherezov V, Liu W (2020) Harnessing the power of an X-ray laser for serial crystallography of membrane proteins crystallized in lipidic cubic phase. IUCrJ 7: 976-984; PDB ID: 6WQA
153 Vrettos EI, Valverde IE, Mascarin A, Pallier PN, Cerofolini L, Fragai M, Parigi G, Hirmiz B, Bekas N, Grob NM, Stylos EK, Shaye H, Borgo MD, Aguilar MI, Magnani F, Syed N, Crook T, Waqif E, Ghazaly E, Cherezov V, Widdop RE, Luchinat C, Michael-Titus AT, Mindt TL, Tzakos AG (2020) Single peptide backbone surrogate mutations to regulate angiotensin GPCR subtype selectivity. Chemistry 26: 10690-10694;
152 Shaye H, Ishchenko A, Lam JH, Han GW, Xue L, Rondard P, Pin J-P, Katritch V, Gati C, Cherezov V (2020) Structural basis of the activation of a metabotropic GABA receptor. Nature 584: 298-303; PDB ID: 6UO8, 6UO9, 6UOA, 6VJM
151 Gusach A, Maslov I, Luginina A, Borshchevskiy V, Mishin A, Cherezov V (2020) Beyond structure: emerging approaches to study GPCR dynamics. Curr Opin Struct Biol 63: 18-25;
150 Zook J, Shekhar M, Hansen D, Conrad C, Grant T, Gupta C, White T, Barty A, Basu S, Zhao Y, Zatsepin N, Ishchenko A, Batyuk A, Gati C, Li C, Galli L, Coe J, Hunter M, Liang M, Weierstall U, Nelson G, James D, Stauch B, Craciunescu F, Thifault D, Liu W, Cherezov V, Singharoy A, Fromme P (2020) XFEL and NMR structures of Francisella lipoprotein reveal conformational space of drug target against tularemia. Structure 28: 540-547; PDB ID: 6PNY
149 Kuklin A, Zabelskii D, Gordeliy I, Teixeira J, Brûlet A, Chupin V, Cherezov V, Gordeliy V (2020) On the origin of the anomalous behavior of lipid membrane properties in the vicinity of the chain-melting phase transition. Sci Rep 10: 5749;
148 Stauch B, Johansson LC, Cherezov V (2020) Structural insights into melatonin receptors. FEBS J 287: 1496-1510;
147 Stein RM, Kang HJ, McCorvy JD, Glatfelter GC, Jones AJ, Che T, Slocum S, Huang X-P, Savych O, Moroz YS, Stauch B, Johansson LC, Cherezov V, Kenakin T, Irwin JJ, Shoichet BK, Roth BL, Dubocovich ML (2020) Virtual discovery of melatonin receptor ligands to modulate circadian rhythms. Nature 579: 609-614;

Publications 2019:
146 Gusach A, Luginina A, Marin E, Brouillette R, Besserer-Offroy E, Longpre JM, Ishchenko A, Popov P, Patel N, Fujimoto T, Maruyama T, Stauch B, Ergasheva M, Romanovskaia D, Stepko A, Kovalev K, Shevtsov M, Gordeliy V, Han GW, Katritch V, Borshchevskiy V, Sarret P, Mishin A, Cherezov V (2019) Structural basis of ligand selectivity and disease mutations in cysteinyl leukotriene receptors. Nat Commun 10: 5573; PDB ID: 6RZ6, 6RZ7, 6RZ8, 6RZ9
145 Ishchenko A, Stauch B, Han GW, Batyuk A, Shiriaeva A, Li C, Zatsepin N, Weierstall U, Liu W, Nango E, Nakane T, Tanaka R, Tono K, Joti Y, Iwata S, Moraes I, Gati C, Cherezov V (2019) Toward G protein-coupled receptor structure-based drug design using X-ray lasers. IUCrJ 6: 1106-1119; PDB ID: 6PRZ, 6PS0, 6PS1, 6PS2, 6PS3, 6PS4, 6PS5, 6PS6, 6PS7, 6PS8
144 Luginina A, Gusach A, Marin E, Mishin A, Brouillette R, Popov P, Shiriaeva A, Besserer-Offroy E, Longpre JM, Lyapina E, Ishchenko A, Patel N, Polovinkin V, Safronova N, Bogorodskiy A, Edelweiss E, Hu H, Weierstall U, Liu W, Batyuk A, Gordeliy V, Han GW, Sarret P, Katritch V, Borshchevskiy V, Cherezov V (2019) Structure-based mechanism of cysteinyl leukotriene receptor inhibition by antiasthmatic drugs. Sci Adv 5: eaax2518; PDB ID: 6RZ4, 6RZ5
143 Mishin A, Gusach A, Luginina A, Marin E, Borshchevskiy V, Cherezov V (2019) An outlook on using serial femtosecond crystallography in drug discovery. Expert Opin Drug Discov 14: 933-945;
142 Zhang Q, Cherezov V (2019) Chemical tools for membrane protein structural biology. Curr Opin Struct Biol 58: 278-285;
141 Johansson LC, Stauch B, McCorvy JD, Han GW, Patel N, Huang X-P, Batyuk A, Gati C, Slocum ST, Li C, Grandner JM, Hao S, Olsen RHJ, Tribo AR, Zaare S, Zhu L, Zatsepin NA, Weierstall U, Yous S, Stevens RC, Liu W, Roth BL, Katritch V, Cherezov V (2019) XFEL structures of the human MT2 melatonin receptor reveal the basis of subtype selectivity. Nature 569: 289-292; PDB ID: 6ME6, 6ME7, 6ME8, 6ME9
140 Stauch B, Johansson LC, McCorvy JD, Patel N, Han GW, Huang X-P, Gati C, Batyuk A, Slocum ST, Ishchenko A, Brehm W, White TA, Michaelian N, Madsen C, Zhu L, Grant TD, Grandner JM, Shiriaeva A, Olsen RHJ, Tribo AR, Yous S, Stevens RC, Weierstall U, Katritch V, Roth BL, Liu W, Cherezov V (2019) Structural basis of ligand recognition at the human MT1 melatonin receptor. Nature 569: 284-288; PDB ID: 6ME2, 6ME3, 6ME4, 6ME5
139 Martin-Garcia JM, Zhu L, Mendez D, Lee M-Y, Chun E, Li C, Hu H, Subramanian G, Kissick D, Ogata C, Henning R, Ishchenko A, Dobson Z, Zhang S, Weierstall U, Spence JCH, Fromme P, Zatsepin NA, Fischetti RF, Cherezov V, Liu W (2019) High-viscosity injector-based pink-beam serial crystallography of microcrystals at a synchrotron radiation source. IUCrJ 6: 412-435; PDB ID: 6MH6, 6MH8
138 Gutierrez MG, Deyell J, White KL, Dalle Ore LC, Cherezov V, Stevens RC, Malmstadt N (2019) The lipid phase preference of the adenosine A2A receptor depends on its ligand binding state. Chem Commun 55: 5724-5727;
137 Audet M, White KL, Breton B, Zarzycka B, Han GW, Lu Y, Gati C, Batyuk A, Popov P, Velasquez J, Manahan D, Hu H, Weierstall U, Liu W, Shui W, Katritch V, Cherezov V, Hanson MA, Stevens RC (2019) Crystal structure of misoprostol bound to the labor inducer prostaglandin E2 receptor. Nat Chem Biol 15: 11-17; PDB ID: 6M9T

Publications 2018:
136 Popov P, Peng Y, Shen L, Stevens RC, Cherezov V, Liu ZJ, Katritch V (2018) Computational design of thermostabilizing point mutations for G protein-coupled receptors. eLife 7: e34729;
135 Abola EE, Weierstall U, Liu W, Cherezov V (2018) Delivery of GPCR Crystals for Serial Femtosecond Crystallography. in Protein Crystallography: Challenges and Practical Solutions Chapter 2: 28-53;
134 Ishchenko A, Gati C, Cherezov V (2018) Structural biology of G protein-coupled receptors: new opportunities from XFELs and cryoEM. Curr Opin Struct Biol 51: 44-52;
133 Stauch B, Cherezov V (2018) Serial Femtosecond Crystallography of G Protein-Coupled Receptors. Annu Rev Biophys 47: 377-397;
132 Che T, Majumdar S, Zaidi SA, Ondachi P, McCorvy JD, Wang S, Mosier PD, Uprety R, Vardy E, Krumm BE, Han GW, Lee MY, Pardon E, Steyaert J, Huang XP, Strachan RT, Tribo AR, Pasternak GW, Carroll FI, Stevens RC, Cherezov V, Katritch V, Wacker D, Roth BL (2018) Structure of the Nanobody-Stabilized Active State of the Kappa Opioid Receptor. Cell 172: 55-67; PDB ID: 6B73
131 Broecker J, Morizumi T, Ou WL, Klingel V, Kuo A, Kissick DJ, Ishchenko A, Lee MY, Xu S, Makarov O, Cherezov V, Ogata CM, Ernst OP (2018) High-throughput in situ X-ray screening of and data collection from protein crystals at room temperature and under cryogenic conditions. Nat Protoc 13: 260-292; PDB ID: 5VRA, 5WJK, 5WKT

Publications 2017:
130 L.C. Johansson, B. Stauch, A. Ishchenko, V. Cherezov (2017) A bright future for serial femtosecond crystallography with XFELs. Trends Biochem Sci 42: 749-762;
129 X.E. Zhou, Y. He, P.W. de Waal, X. Gao, Y. Kang, N. Van Eps, Y. Yin, K. Pal, D. Goswami, T.A. White, A. Barty, N.R. Latorraca, H.N. Chapman, W.L. Hubbell, R.O. Dror, R.C. Stevens, V. Cherezov, V.V. Gurevich, P.R. Griffin, O.P. Ernst, K. Melcher, H.E. Xu (2017) Identification of phosphorylation codes for arrestin recruitment by G protein-coupled receptors. Cell 170: 457-469; PDB ID: 5W0P
128 A. Ishchenko, D. Wacker, M. Kapoor, A. Zhang, G.W. Han, S. Basu, N. Patel, M. Messerschmidt, U. Weierstall, W. Liu, V. Katritch, B.L. Roth, R.C. Stevens, V. Cherezov (2017) Structural insights into the extracellular recognition of the human serotonin 2B receptor by an antibody. Proc Natl Acad Sci USA 114: 8223-8228; PDB ID: 5TUD
127 P.S. Padayatti, J.H. Leung, P. Mahinthichaichan, E. Tajkhorshid, A. Ishchenko, V. Cherezov, S.M. Soltis, J.B. Jackson, C.D. Stout, R.B. Gennis, Q. Zhang (2017) Critical role of water molecules in proton translocation by the membrane-bound transhydrogenase. Structure 25: 1111-1119; PDB ID: 5UNI
126 Y. Zheng, G.W. Han, R. Abagyan, B. Wu, R.C. Stevens, V. Cherezov, I. Kufareva, T.M. Handel (2017) Structure of CC chemokine receptor 5 with a potent chemokine angagonist reveals mechanisms of chemokine recognition and molecular mimicry by HIV. Immunity 46: 1005-1017; PDB ID: 5UIW
125 H. Zhang, A. Qiao, D. Yang, A. Dai, C. deGraaf, S. Reedtz-Runge, V. Dharmarajan, H. Zhang, G.W. Han, T.D. Grant, R.G. Sierra, U. Weierstall, G. Nelson, W. Liu, Y. Wu, L. Ma, X. Cai, G. Lin, X. Wu, Z. Geng, Y. Dong, G. Song, R.P. Griffin, J. Lau, V. Cherezov, H. Yang, M.A. Hanson, R.C. Stevens, Q. Zhao,H. Jiang, M.W. Wang, B. Wu (2017) Structure of the full-length glucagon class B G protein-coupled receptor. Nature 546: 259-264; PDB ID: 5XF1, 5XEZ,
124 A. Ishchenko, E.E. Abola, V. Cherezov (2017) Crystallization of membrane proteins: an overview. Methods Mol Biol 1607: 117-141;
123 A. Ishchenko, L. Peng, E. Zinovev, A. Vlasov, S.C. Lee, A. Kuklin, A. Mishin, V. Borshchevskiy, Q. Zhang, V. Cherezov (2017) Chemically stable lipids for membrane protein crystallization. Cryst Growth Des 17: 3502-3511; PDB ID: 5VN7, 5VN9
122 J.M. Martin-Garcia, C.E. Conrad, G. Nelson, N. Stander, N.A. Zatsepin, J. Zook, L. Zhu, J. Geiger, E. Chun, D. Kissick, M.C. Hilgart, C. Ogata, A. Ishchenko, N. Nagaratnam, S. Roy-Chowdhury, J. Coe, G. Subramaniam, A. Schaffer, D. James, G. Ketwala, N. Venugopalan, S. Xu, S. Corcoran, D. Ferguson, U. Weierstall, J.C.H. Spence, V. Cherezov, P. Fromme, R.F. Fischetti, W. Liu (2017) Serial millisecond crystallography of membrane and soluble protein microcrystals using synchrotron radiation. IUCrJ 4: 439-454; PDB ID: 5UVL, 5UVK, 5UVJ, 5UVI,
121 X. Zhang, F. Zhao, Y. Wu, J. Yang, G.W. Han, S. Zhao, A. Ishchenko, L. Ye, X. Lin, K. Ding, V. Dharmarajan, P.R. Griffin, C. Gati, G. Nelson, M.S. Hunter, M.A. Hanson, V. Cherezov, R.C. Stevens, W. Tan, H. Tao, F. Xu (2017) Crystal structure of a multi-domain human smoothened receptor in complex with a super stabilizing ligand. Nat Commun 8: 15383; PDB ID: 5V56, 5V57,
120 I. Melnikov, V. Polovinkin, K. Kovalev, I. Gushchin, M. Shevtsov, V. Shevchenko, A. Mishin, A. Alekseev, F. Rodriguez-Valera, V. Borshchevskiy, V. Cherezov, G.A. Leonard, V. Gordeliy, A. Popov (2017) Fast iodide-SAD phasing for high-throughput membrane protein structure determination. Sci Adv 3: e1602952; PDB ID: 5JTB, 5JSI, 5JRF, 5JGP
119 H. Zhang, G.W. Han, A. Batyuk, A. Ishchenko, K.I. White, N. Patel, A. Sadybekov, B. Zamlynny, M.T. Rudd, K. Hollenstein, A. Tolstikova, T.A. White, M.S. Hunter, U. Weierstall, W. Liu, K. Babaoglu, E.L. Moore, R.D. Katz, J.M. Shipman, M. Garcia-Calvo, S. Sharma, P. Sheth, S.M. Soisson, R.C. Stevens, V. Katritch, V. Cherezov (2017) Structural basis for selectivity and diversity in angiotensin II receptors. Nature 544: 327-332; PDB ID: 5UNH, 5UNG, 5UNF

Publications 2016:
118 Y. Zheng, L. Qin, N.V. Zacarias, H. de Vries, G.W. Han, M. Gustavsson, M. Dabros, C. Zhao, R.J. Cherney, P. Carter, D. Stamos, R. Abagyan, V. Cherezov, R.C. Stevens, A.P. IJzerman, L.H. Heitman, A. Tebben, I. Kufareva, T.M. Handel (2016) Structure of CC chemokine receptor 2 with orthosteric and allosteric antagonists. Nature 540: 458-461; PDB ID: 5T1A
117 A. Batyuk, L. Galli, A. Ishchenko, G.W. Han, C. Gati, P.A. Popov, M.Y. Lee, B. Stauch, T.A. White, A. Barty, A. Aquila, M.S. Hunter, M. Liang, S. Boutet, M. Pu, Z.J. Liu, G. Nelson, D. James, C. Li, Y. Zhao, J.C. Spence, W. Liu, P. Fromme, V. Katritch, U. Weierstall, R.C. Stevens, V. Cherezov (2016) Native phasing of X-ray free-electron laser data for a G protein-coupled receptor. Sci Adv 2: e1600292; PDB ID: 5K2A, 5K2B, 5K2C, 5K2D
116 A. Ishchenko, V. Cherezov, W. Liu (2016) Preparation and delivery of protein microcrystals in lipidic cubic phase for serial femtosecond crystallography. J Vis Exp 115: e54463;
115 L. Zhu, U. Weierstall, V. Cherezov, W. Liu (2016) Serial femtosecond crystallography of membrane proteins, in The Next Generation in Membrane Protein Structure Determination. I. Moraes, Editor. Adv Exp Med Biol 922: 151-160;
114 T.A. White, A. Barty, W. Liu, A. Ishchenko, H. Zhang, C. Gati, N.A. Zatsepin, S. Basu, D. Oberthuer, M. Metz, K.R. Beyerlein, C.H. Yoon, O.M. Yefanov, D. James, D. Wang, M. Messerschmidt, J.E. Koglin, S. Boutet, U. Weierstall, V. Cherezov (2016) Serial femtosecond crystallography datasets from G protein-coupled receptors. Sci Data 3: 160057;
113 X.E. Zhou, X. Gao, A. Barty, Y. Kang, Y. He, W. Liu, A. Ishchenko, T.A. White, O. Yefanov, G.W. Han, Q. Xu, P.W. de Waal, K.M. Suino-Powell, S. Boutet, G.J. Williams, M. Wang, D. Li, M. Caffrey, H.N. Chapman, J.C. Spence, P. Fromme, U. Weierstall, R.C. Stevens, V. Cherezov, K. Melcher, H.E. Xu (2016) X-ray laser diffraction for structure determination of the rhodopsin-arrestin complex. Sci Data 3: 160021; PDB ID: 5DGY
112 A. Heifetz, E. Chudyk, L. Gleave, M. Aldeghi, V. Cherezov, D.G. Fedorov, P.G. Biggin, M. Bodkin (2016) The Fragment Molecular Orbital Method Reveals New Insight into the Chemical Nature of GPCR-Ligand Interactions. J Chem Inf Model 56: 159-172;

Publications 2015:
111 D. Li, P.J. Stansfeld, M.S.P. Sansom, A. Keogh, L. Vogeley, N. Howe, J.A. Lyons, D. Aragao, P. Fromme, R. Fromme, S. Basu, I. Grotjohann, C. Kupitz, K. Rendek, U. Weierstall, N.A. Zatsepin, V. Cherezov, W. Liu, S. Bandaru, N.J. English, C. Gati, A. Barty, O. Yefanov, H.N. Chapman, K. Diederichs, M. Messerschmidt, S. Boutet, G.J. Williams, M.M. Seibert, M. Caffrey (2015) Ternary structure reveals mechanism of a membrane diacylglycerol kinase. Nat Commun 6: 10140; PDB ID: 4UXX, 4UXW, 4UYO, 4UXZ
110 A. Bogorodskiy, F. Frolov, A. Mishin, E. Round, V. Polovinkin, V. Cherezov, V. Gordeliy, G. Bueldt, T. Gensch, V. Borshchevskiy (2015) Nucleation and Growth of Membrane Protein Crystals in Meso - a Fluorescence Microscopy Study. Cryst Growth Des 15: 5656-5660;
109 H. Zhang, H. Unal, R. Desnoyer, G.W. Han, N. Patel, V. Katritch, S.S. Karnik, V. Cherezov, R.C. Stevens (2015) Structural Basis for Ligand Recognition and Functional Selectivity at Angiotensin Receptor. J Biol Chem 290: 29127-29139; PDB ID: 4ZUD
108 R.L. Miller, A.A. Thompson, C. Trapella, R. Guerrini, D. Malfacini, N. Patel, G.W. Han, V. Cherezov, G. Calo, V. Katritch, R.C. Stevens (2015) The Importance of Ligand-Receptor Conformational Pairs in Stabilization: Spotlight on the N/OFQ G Protein-Coupled Receptor. Structure 23: 2291-2299; PDB ID: 5DHH, 5DHG
107 R.M. Lawrence, C.E. Conrad, N.A. Zatsepin, T.D. Grant, H. Liu, D. James, G. Nelson, G. Subramanian, A. Aquila, M.S. Hunter, M. Liang, S. Boutet, J. Coe, J.C.H. Spence, U. Weierstall, W. Liu, P. Fromme, V. Cherezov, B.G. Hogue (2015) Serial femtosecond X-ray diffraction of enveloped virus microcrystals. Struct Dyn 2: 041720;
106 R. Fromme, A. Ishchenko, M. Metz, S.R. Chowdhury, S. Basu, S. Boutet, P. Fromme, T.A. White, A. Barty, J.C. Spence, U. Weierstall, W. Liu, V. Cherezov (2015) Serial femtosecond crystallography of soluble proteins in lipidic cubic phase. IUCrJ 2: 541-551; PDB ID: 4ZIX, 4ZIZ
105 Y. Kang, X.E. Zhou, X. Gao, Y. He, W. Liu, A. Ishchenko, A. Barty, T.A. White, O. Yefanov, G.W. Han, Q. Xu, P.W. de Waal, J. Ke, M.H. Tan, C. Zhang, A. Moeller, G.M. West, B.D. Pascal, N. Van Eps, L.N. Caro, S.A. Vishnivetskiy, R.J. Lee, K.M. Suino-Powell, X. Gu, K. Pal, J. Ma, X. Zhi, S. Boutet, G.J. Williams, M. Messerschmidt, C. Gati, N.A. Zatsepin, D. Wang, D. James, S. Basu, S. Roy-Chowdhury, C.E. Conrad, J. Coe, H. Liu, S. Lisova, C. Kupitz, I. Grotjohann, R. Fromme, Y. Jiang, M. Tan, H. Yang, J. Li, M. Wang, Z. Zheng, D. Li, N. Howe, Y. Zhao, J. Standfuss, K. Diederichs, Y. Dong, C.S. Potter, B. Carragher, M. Caffrey, H. Jiang, H.N. Chapman, J.C. Spence, P. Fromme, U. Weierstall, O.P. Ernst, V. Katritch, V.V. Gurevich, P.R. Griffin, W.L. Hubbell, R.C. Stevens, V. Cherezov, K. Melcher, H.E. Xu (2015) Crystal structure of rhodopsin bound to arrestin by femtosecond X-ray laser. Nature 523: 561-567; PDB ID: 4ZWJ
104 C.E. Conrad, S. Basu, D. James, D. Wang, A. Schaffer, S. Roy-Chowdhury, N.A. Zatsepin, A. Aquila, J. Coe, C. Gati, M.S. Hunter, J.E. Koglin, C. Kupitz, G. Nelson, G. Subramanian, T.A. White, Y. Zhao, J. Zook, S. Boutet, V. Cherezov, J.C.H. Spence, R. Fromme, U. Weierstall, P. Fromme (2015) A novel inert crystal delivery medium for serial femtosecond crystallography. IUCrJ 2: 421-430; PDB ID: 4Z8K
103 H. Zhang, H. Unal, C. Gati, G.W. Han, W. Liu, N.A. Zatsepin, D. James, D. Wang, G. Nelson, U. Weierstall, M.R. Sawaya, Q. Xu, M. Messerschmidt, G.J. Williams, S. Boutet, O.M. Yefanov, T.A. White, C. Wang, A. Ishchenko, K.C. Tirupula, R. Desnoyer, J. Coe, C.E. Conrad, P. Fromme, R.C. Stevens, V. Katritch, S.S. Karnik, V. Cherezov (2015) Structure of the Angiotensin Receptor Revealed by Serial Femtosecond Crystallography. Cell 161: 833-844; PDB ID: 4YAY
102 A. Heifetz, G.F.X. Schertler, R. Seifert, C.G. Tate, P.M. Sexton, V.V. Gurevich, D. Fourmy, V. Cherezov, F.H. Marshall, R.I. Storer, I. Moraes, I.G. Tikhonova, C.S. Tautermann, P. Hunt, T. Ceska, S. Hodgson, M.J. Bodkin, S. Singh, R.J. Law, P.C. Biggin (2015) GPCR structure, function, drug discovery and crystallography: report from Academia-Industry International Conference (UK Royal Society) Chicheley Hall, 1-2 September 2014. Naunyn-Schmiedeberg's Arch Pharmacol 388: 883-903;
101 G. Fenalti, E.E. Abola, C. Wang, B. Wu, V. Cherezov (2015) Fluorescence recovery after photobleaching in Lipidic Cubic Phase (LCP-FRAP): a precrystallization assay for membrane proteins. Met Enzymol 557: 417-437;
100 D. Zhang, Z.G. Gao, K. Zhang, E. Kisselev, S. Crane, J. Wang, S. Paoletta, C. Yi, L. Ma, W. Zhang, G.W. Han, H. Liu, V. Cherezov, V. Katritch, J. Jiang, R.C. Stevens, K.A. Jacobson, Q. Zhao, B. Wu (2015) Two disparate ligand-binding sites in the human P2Y1 receptor Nature 520: 317-321; PDB ID: 4XNV, 4XNW
99 G. Fenalti, N.A. Zatsepin, C. Betti, P. Giguere, G.W. Han, A. Ishchenko, W. Liu, K. Guillemyn, H. Zhang, D. James, D. Wang, U. Weierstall, J.C.H. Spence, S. Boutet, M. Messerschmidt, G.J. Williams, C. Gati, O.M. Yefanov, T.A. White, D. Oberthuer, M. Metz, C.H. Yoon, A. Barty, H.N. Chapman, S. Basu, J. Coe, C.E. Conrad, R. Fromme, P. Fromme, D. Tourwe, P.W. Schiller, B.L. Roth, S. Ballet, V. Katritch, R.C. Stevens, V. Cherezov (2015) Structural basis for bifunctional peptide recognition at human delta-opioid receptor. Nat Struct Mol Biol 22: 265-268; PDB ID: 4RWA, 4RWD
98 L. Qin, I. Kufareva, L.G. Holden, C. Wang, Y. Zheng, C. Zhao, G. Fenalti, H. Wu, G.W. Han, V. Cherezov, R. Abagyan, R.C. Stevens, T.M. Handel (2015) Crystal structure of the chemokine receptor CXCR4 in complex with a viral chemokine. Science 347: 1117-1122; PDB ID: 4RWS
97 P. Nogly, D. James, D. Wang, T.A. White, N. Zatsepin, A. Shilova, G. Nelson, H. Liu, L. Johansson, M. Heymann, K. Jaeger, M. Metz, C. Wickstrand, W. Wu, P. Bath, P. Berntsen, D. Oberthuer, V. Panneels, V. Cherezov, H. Chapman, G. Schertler, R. Neutze, J. Spence, I. Moraes, M. Burghammer, J. Standfuss, U. Weierstall (2015) Lipidic cubic phase serial millisecond crystallography using synchrotron radiation. IUCrJ 2: 168-176; PDB ID: 4X31, 4X32
96 V. Isberg, C. de Graaf, A. Bortolato, V. Cherezov, V. Katritch, F.H. Marshall, S. Mordalski, J. Pin, R.C. Stevens, G. Vriend, D.E. Gloriam (2015) Generic GPCR residue numbers - aligning topology maps while minding the gaps. Trends Pharmacol Sci 36: 22-31;

Publications 2014:
95 D.L. Gater, O. Saurel, I. Iordanov, W. Liu, V. Cherezov, A. Milon (2014) Two classes of cholesterol binding sites for the b2AR revealed by thermostability and NMR Biophysics J 107: 2305-2312;
94 M.A. Goren, T. Morizumi, I. Menon, J.S. Joseph, J.S. Dittman, V. Cherezov, R.C. Stevens, O.P. Ernst, A.K. Menon (2014) Constitutive phospholipid scramblase activity of a G protein-coupled receptor. Nat Commun 5: 5115;
93 W. Liu, A. Ishchenko, V. Cherezov (2014) Preparation of microcrystals in lipidic cubic phase for serial femtosecond crystallography. Nat Protoc 9: 2123-2134;
92 C. Wang, H. Wu, T. Evron, E. Vardy, G.W. Han, X.P., Huang, S.J. Hufeisen, T.J. Mangano, D.J. Urban, V. Katritch, V. Cherezov, M.G. Caron, B.L. Roth, R.C. Stevens (2014) Structural basis for Smoothened receptor modulation and chemoresistance to anticancer drugs. Nat Commun 5: 4355; PDB ID: 4N4W, 4QIN, 4QIM
91 W. Liu, D. Wacker, C. Wang, E. Abola, V. Cherezov (2014) Femtosecond crystallography of membrane proteins in the lipidic cubic phase. Phil Trans R Soc B 369: 20130314;
90 A. Ishchenko, E. Abola, V. Cherezov (2014) Lipidic Cubic Phase Technologies for Structural Studies of Membrane Proteins. in Membrane Protein Production for Structural Analysis, ed. I. Mus-Veteau, pages 289-314 (Springer);
89 J. Zhang, K. Zhang, Z.G. Gao, S. Paoletta, D. Zhang, G.W. Han, T. Li, L. Ma, W. Zhang, C.E. Muller, H. Yang, H. Jiang, V. Cherezov, V. Katritch, K.A. Jacobson, R.C. Stevens, B. Wu, Q.Zhao (2014) Agonist-bound structure of the human P2Y12 receptor. Nature 509: 119-122; PDB ID: 4PXZ, 4PY0
88 K. Zhang, J. Zhang, Z.G. Gao, D. Zhang, L. Zhu, G.W. Han, S.M. Moss, S. Paoletta, E. Kiselev, W. Lu, G. Fenalti, W. Zhang, C.E. Muller, H. Yang, H. Jiang, V. Cherezov, V. Katritch, K.A. Jacobson, R.C. Stevens, B. Wu, Q.Zhao (2014) Structure of the human P2Y12 receptor in complex with an antithrombotic drug. Nature 509: 115-118; PDB ID: 4NTJ
87 V. Katritch, G. Fenalti, E.E. Abola, B.L. Roth, V. Cherezov, R.C. Stevens (2014) Allosteric sodium in class A GPCR signaling. Trends Biochem Sci 39: 233-244;
86 H. Wu, C. Wang, K.J. Gregory, G.W. Han, H.P. Cho, Y. Xia, C.M. Niswender, V. Katritch, J. Meiler, V. Cherezov, P.J. Conn, R.C. Stevens (2014) Structure of a class C GPCR metabotropic glutamate receptor 1 bound to an allosteric modulator. Science 344: 58-64; PDB ID: 4OR2
85 U. Weierstall, D. James, C. Wang, T.A. White, D. Wang, W. Liu, J.C. Spence, R.B. Doak, G. Nelson, P. Fromme, R. Fromme, I. Grotjohann, C. Kupitz, N.A. Zatsepin, H. Liu, S. Basu, D. Wacker, G.W. Han, V. Katritch, S. Boutet, M. Messerschmidt, G.J. Williams, J.E. Koglin, M.M. Seibert, M. Klinker, C. Gati, R.L., Shoeman, A. Barty, H.N. Chapman, R.A. Kirian, K.R. Beyerlein, R.C. Stevens, D. Li, S.T. Shah, N. Howe, M. Caffrey, V. Cherezov (2014) Lipidic cubic phase injector facilitates membrane protein serial femtosecond crystallography. Nat Commun 5: 3309; PDB ID: 4O9R
84 G. Fenalti, P.M. Giguere, V. Katritch, X.P. Huang, A.A. Thompson, V. Cherezov, B.L. Roth, R.C. Stevens (2014) Molecular control of delta-opioid receptor signalling. Nature 506: 191-196; PDB ID: 4N6H
83 K. Niescierowicz, L. Caro, V. Cherezov, M. Vivaudou, C.J. Moreau (2014) Functional assay for T4 lysozyme-engineered G protein-coupled receptors with an ion channel reporter. Structure 22: 149-155;

Publications 2013:
82 W. Liu, D. Wacker, C. Gati, G.W. Han, D. James, D. Wang, G. Nelson, U. Weierstall, V. Katritch, A. Barty, N.A. Zatsepin, D. Li, M. Messerschmidt, S. Boutet, G.J. Williams, J.E. Koglin, M.M. Seibert, C. Wang, S.T.A. Shah, S. Basu, R. Fromme, C. Kupitz, K.N. Rendek, I. Grotjohann, P. Fromme, R.A. Kirian, K.R. Beyerlein, T.A. White, H.N. Chapman, M. Caffrey, J.C.H. Spence, R.C. Stevens, V. Cherezov (2013) Serial femtosecond crystallography of G protein-coupled receptors. Science 342: 1521-1524; PDB ID: 4NC3
81 H. Gutierrez-de-Teran, A. Massink, D. Rodriguez, W. Liu, G.W. Han, G.S. Joseph, I. Katritch, L.H. Heitman, L. Xia, A.P. IJzerman, V. Cherezov, V. Katritch, R.C. Stevens (2013) The role of a sodium ion binding site in the allosteric modulation of the A2A adenosine G Protein-Coupled Receptor. Structure 21: 2175-2185;
80 Q. Tan, Y. Zhu, J. Li, Z. Chen, G.W. Han, I. Kufareva, T. Li, L. Ma, G. Fenalti, J. Li, W. Zhang, X. Xie, H. Yang, H. Jiang, V. Cherezov, H. Liu, R.C. Stevens, Q. Zhao, B. Wu (2013) Structure of the CCR5 chemokine receptor-HIV entry inhibitor maraviroc complex. Science 341: 1387-1390; PDB ID: 4MBS
79 R. Lane, P. Chubukov, W. Liu, M. Canals, V. Cherezov, R. Abagyan, R.C. Stevens, V. Katritch (2013) Structure-based ligand discovery targeting orthosteric and allosteric pockets of dopamine receptors. Mol Pharmacol 84: 794-807;
78 F.Y. Siu, M. He, C. de Graaf, G.W. Han, D. Yang, Z. Zhang, C. Zhou, Q. Xu, D. Wacker, J.S. Joseph, W. Liu, J. Lau, V. Cherezov, V. Katritch, M.W. Wang and R.C. Stevens (2013) Structure of the human glucagon class B G-protein-coupled receptor. Nature 499: 444-449; PDB ID: 4L6R
77 J.T. Madden, S.J. Toth, C.M. Dettmar, J.A. Newman, R.A. Oglesbee, H.G. Hedderich, R.M. Everly, M. Becker, J.A. Ronau, S.K. Buchanan, V. Cherezov, M.E. Morrow, S. Xu, D. Ferguson, O. Makarov, C. Das, R. Fischetti, and G.J. Simpson (2013) Integrated nonlinear optical imaging microscope for on-axis crystal detection and centering at a synchrotron beamline. J. Synchrotron Radiat. 20: 531-540;
76 D.L. Gater, V. Reat, G. Czaplicki, O. Saurel, A. Milon, and V. Cherezov (2013) Hydrogen Bonding of Cholesterol in the Lipidic Cubic Phase. Langmuir 29: 8031-8038;
75 C. Wang, H. Wu, V. Katritch, G.W. Han, X.-P. Huang, W. Liu, F.Y. Siu, B.L. Roth, V. Cherezov and R.C. Stevens (2013) Structure of the human smoothened receptor bound to an antitumour agent. Nature 497: 338-343; PDB ID: 4JKV
74 D. Wacker, C. Wang, V. Katritch, G.W. Han, X.-P. Huang, E. Vardy, J.D. McCorvy, Y. Jiang, M. Chu, F.Y. Siu, W. Liu, H.E. Xu, V. Cherezov, B.L. Roth and R.C. Stevens (2013) Structural features for functional selectivity at serotonin receptors. Science 340: 615-619; PDB ID: 4IB4
73 C. Wang, Y. Jiang, J. Ma, H. Wu, D. Wacker, V. Katritch, G.W. Han, W. Liu, X.-P. Huang, E. Vardy, J.D. McCorvy, X. Gao, E.X. Zhou, K. Melcher, C. Zhang, F. Bai, H. Yang, L. Yang, H. Jiang, B.L. Roth, V. Cherezov, R.C. Stevens and H.E. Xu (2013) Structural basis for molecular recognition at serotonin receptors. Science 340: 610-614; PDB ID: 4IAR, 4IAQ
72 D.J. Kissick, C.M. Dettmar, M. Becker, A.M. Mulichak, V. Cherezov, S.L. Ginell, K.P. Battail, L.J. Keefe, R.F. Fischetti, G.J. Simpson (2013) Towards protein-crystal centering using second-harmonic generation (SHG) microscopy. Acta Crystallogr D Biol Crystallogr 69: 843-851; PDB ID: 4DC5, 4DC6, 4DC7, 4DC8
71 R.C. Stevens, V. Cherezov, V. Katritch, R. Abagyan, P. Kuhn, H. Rosen and K. Wuthrich (2013) The GPCR Network: a large-scale collaboration to determine human GPCR structure and function. Nat Rev Drug Discov 12: 25-34;
70 V. Katritch, V. Cherezov, and R.C. Stevens (2013) Structure-Function of the G Protein-Coupled Receptors Superfamily. Annu Rev Pharmacol Toxicol 53: 531-556;

Publications 2012:
69 J.S.Santos, G.A. Asmar-Rovira, G.W.Han, W.Liu, R.Syeda, V. Cherezov, K.A. Baker, R.C. Stevens and M. Montal (2012) Crystal structure of a voltage-gated K+ channel pore module in a closed state in lipid membranes. J Biol Chem 287: 43063-43070; PDB ID: 4H33, 4H37
68 J.S. Joseph, E.E. Abola, and V. Cherezov (2012) Structural Insights into Cholesterol Interactions with G Protein-Coupled Receptors. In: Cholesterol Regulation of Ion Channels and Receptors, Eds. I. Levitan and F.J. Barrantes. Chapter 11: 231-253. John Wiley & Sons;
67 E.E. Abola, V. Cherezov, and R.C. Stevens (2012) X-ray crystallography: crystallization. In: Comprehensive Biophysics. Eds. E.H. Egelman, H.J. Dyson. Volume 1: 34-63. Academic Press: Oxford;
66 W. Liu, E. Chun, A.A. Thompson, P. Chubukov, F. Xu, V. Katritch, G.W. Han, C.B. Roth, L.H. Heitman, A.P. IJzerman, V. Cherezov and R.C. Stevens (2012) Structural basis for allosteric regulation of GPCRs by sodium ions. Science 337: 232-236; PDB ID: 4EIY
65 J.W. Fairman, N. Dautin, D. Wojtowicz, W. Liu, N. Noinaj, T.J. Barnard, E. Udho, T.M. Przytycka, V. Cherezov and S.K. Buchanan (2012) Crystal structures of the outer membrane domain of intimin and invasin from enterohemorrhagic E. coli and enteropathogenic Y. pseudotuberculosis. Structure 20: 1233-1243; PDB ID: 4E1S, 4E1T
64 E. Chun, A.A. Thompson, W. Liu, C.R. Roth, M.T. Griffith, V. Katritch, J. Kunken, F. Xu, V. Cherezov, M.A. Hanson and R.C. Stevens (2012) Fusion partner toolchest for the stabilization and crystallization of G protein-coupled receptors Structure 20: 967-976;
63 A.A. Thompson, W. Liu, E. Chun, V. Katritch, H. Wu, E. Vardy, X.-P. Huang, C. Trapella, R. Guerrini, G. Calo, B.L. Roth, V. Cherezov and R.C. Stevens (2012) Structure of the nociceptin/orphanin FQ receptor in complex with a peptide mimetic Nature 485: 395-399; PDB ID: 4EA3
62 H. Wu, D. Wacker, M. Mileni, V. Katritch, G.W. Han, E. Vardy, W. Liu, A.A. Thompson, X.-P. Huang, F.I. Carroll, S.W. Mascarella, R.B. Westkaemper, P.D. Mosier, B.L. Roth, V. Cherezov and R.C. Stevens (2012) Structure of the human k-opioid receptor in complex with JDTic Nature 485: 327-332; PDB ID: 4DJH
61 V. Katritch, V. Cherezov and R.C. Stevens (2012) Diversity and modularity of G protein-coupled receptor structures TIPS 33: 17-27;

Publications 2011:
60 A.A. Thompson, J.J. Liu, E. Chun, D. Wacker, H. Wu, V. Cherezov and R.C. Stevens (2011) GPCR stabilization using the bicelle-like architecture of mixed sterol-detergent micelles Methods 55: 310-317;
59 J.S. Joseph, W. Liu, J. Kunken, T.M. Weiss, H. Tsuruta, V. Cherezov (2011) Characterization of lipid matrices for membrane protein crystallization by high-throughput small angle X-ray scattering Methods 55: 342-349;
58 V. Cherezov (2011) Lipidic cubic phase technologies for membrane protein structural studies Curr Opin Struct Biol 21: 559-566;
57 T. Tiefenbrunn, W. Liu, Y. Chen, V. Katritch, C.D. Stout, J.A. Fee and V. Cherezov (2011) High resolution structure of the ba3 cytochrome c oxidase from Thermus thermophilus in a lipidic environment PLoS One 6: e22348; PDB ID: 3S8F, 3S8G
56 T. Shimamura, M. Shiroshi, S. Weyand, H. Tsujimoto, G. Winter, V. Katritch, R. Abagyan, V. Cherezov, W. Liu, G. W. Han, T. Kobayashi, R. C. Stevens and S. Iwata (2011) Structure of the human histamine H1 receptor complex with doxepin Nature 475: 65-70; PDB ID: 3RZE
55 F. Xu, H. Wu, V. Katritch, G. W. Han, K. A. Jacobson, Z.-G. Gao, V. Cherezov and R. C. Stevens (2011) Structure of an agonist-bound human A2A adenosine receptor Science 332: 322-327; PDB ID: 3QAK
54 F. Xu, W.Liu, M. A. Hanson, R. C. Stevens and V. Cherezov (2011) Development of an automated high throughput LCP-FRAP assay to guide membrane protein crystallization in lipid mesophases Cryst Growth Des 11: 1193-1201;
53 W. Liu, and V. Cherezov (2011) Crystallization of membrane proteins in lipidic mesophases J Vis Exp 49: e2501;

Publications 2010:
52 E. Y. Chien, W. Liu, Q. Zhao, V. Katritch, G. W. Han, M. A. Hanson, L. Shi, A. H. Newman, J. A. Javitch, V. Cherezov and R. C. Stevens (2010) Structure of the human dopamine D3 receptor in complex with a D2/D3 selective antagonist Science 330: 1091-5 ; PDB ID: 3PBL
51 B. Wu, E. Y. Chien, C. D. Mol, G. Fenalti, W. Liu, V. Katritch, R. Abagyan, A. Brooun, P. Wells, F. C. Bi, D. J. Hamel, P. Kuhn, T. M. Handel, V. Cherezov and R. C. Stevens (2010) Structures of the CXCR4 chemokine GPCR with small-molecule and cyclic peptide antagonists Science 330: 1066-71 ; PDB ID: 3ODU, 3OE0, 3OE6, 3OE8, 3OE9
50 V. Cherezov, E. Abola and R. C. Stevens (2010) Recent Progress in the Structure Determination of GPCRs, a Membrane Protein Family with High Potential as Pharmaceutical Targets Methods Mol Biol 654: 141-68 ;
49 D. Wacker, G. Fenalti, M. A. Brown, V. Katritch, R. Abagyan, V. Cherezov and R. C. Stevens (2010) Conserved binding mode of human beta2 adrenergic receptor inverse agonists and antagonist revealed by X-ray crystallography J Am Chem Soc 132: 11443-5 ; PDB ID: 3NY8, 3NY9, 3NYA
48 W. Liu, M. A. Hanson, R. C. Stevens and V. Cherezov (2010) LCP-Tm: an assay to measure and understand stability of membrane proteins in a membrane environment Biophys J 98: 1539-48 ;
47 D. J. Kissick, E. J. Gualtieri, G. J. Simpson and V. Cherezov (2010) Nonlinear optical imaging of integral membrane protein crystals in lipidic mesophases Anal Chem 82: 491-7 ;

Publications 2009:
46 M. Caffrey and V. Cherezov (2009) Crystallizing membrane proteins using lipidic mesophases Nat Protoc 4: 706-731 ;
45 V. Cherezov, M. A. Hanson, M. T. Griffith, M. C. Hilgart, R. Sanishvili, V. Nagarajan, S. Stepanov, R. F. Fischetti, P. Kuhn and R. C. Stevens (2009) Rastering strategy for screening and centring of microcrystal samples of human membrane proteins with a sub-10 microm size X-ray synchrotron beam J R Soc Interface 6 Suppl 5: S587-97 ;
44 V. Katritch, V. Cherezov, M. A. Hanson, R. B. Roth, M. Yeager and R. Abagyan (2009) Analysis of full and partial agonists binding to beta(2)-adrenergic receptor suggests a role of transmembrane helix V in agonist-specific conformational changes J Mol Recognit 22: 307-318 ;

Publications 2008:
43 V. Cherezov, N. Hofer, D. M. Szebenyi, O. Kolaj, J. G. Wall, R. Gillilan, V. Srinivasan, C. P. Jaroniec and M. Caffrey (2008) Insights into the mode of action of a putative zinc transporter CzrB in Thermus thermophilus Structure 16: 1378-88 ; PDB ID: 3BYP, 3BYR
42 V. Cherezov, J. Liu, M. A. Hanson, M. T. Griffith and R. C. Stevens (2008) LCP-FRAP assay for pre-screening membrane proteins for in meso crystallization Cryst Growth Des 8: 4307-4315 ;
41 V. Cherezov, W. Liu, J. P. Derrick, B. Luan, A. Aksimentiev, V. Katritch and M. Caffrey (2008) In meso crystal structure and docking simulations suggest an alternative proteoglycan binding site in the OpcA outer membrane adhesin Proteins 71: 24-34 ; PDB ID: 2VDF
40 M. A. Hanson, V. Cherezov, M. T. Griffith, C. B. Roth, V. P. Jaakola, E. Y. Chien, J. Velasquez, P. Kuhn and R. C. Stevens (2008) A Specific Cholesterol Binding Site Is Established by the 2.8 A Structure of the Human beta(2)-Adrenergic Receptor Structure 16: 897-905 ; PDB ID: 3D4S
39 V. P. Jaakola, M. T. Griffith, M. A. Hanson, V. Cherezov, E. Y. Chien, J. R. Lane, A. P. Ijzerman and R. C. Stevens (2008) The 2.6 Angstrom Crystal Structure of a Human A2A Adenosine Receptor Bound to an Antagonist Science 322: 1211-1217 ; PDB ID: 3EML

Publications 2007:
38 V. Cherezov and M. Caffrey (2007) Membrane protein crystallization in lipidic mesophases. A mechanism study using X-ray microdiffraction Faraday Discuss 136: 195-212; discussion 213-29 ;
37 V. Cherezov and M. Caffrey (2007) Miniaturization and automation for high-throughput membrane protein crystallization in lipidic mesophases N. E. Chayen Protein crystallization strategies for structural genomics San Diego International University Line
36 V. Cherezov, D. M. Rosenbaum, M. A. Hanson, S. G. Rasmussen, F. S. Thian, T. S. Kobilka, H. J. Choi, P. Kuhn, W. I. Weis, B. K. Kobilka and R. C. Stevens (2007) High-resolution crystal structure of an engineered human beta2-adrenergic G protein-coupled receptor Science 318: 1258-65 ; PDB ID: 2RH1
35 N. Hofer, O. Kolaj, H. Li, V. Cherezov, R. Gillilan, J. G. Wall and M. Caffrey (2007) Crystallization and preliminary X-ray diffraction analysis of a soluble domain of the putative zinc transporter CzrB from Thermus thermophilus Acta Crystallogr Sect F Struct Biol Cryst Commun 63: 673-7 ;
34 A. Peddi, L. Muthusubramaniam, Y. F. Zheng, V. Cherezov, Y. Misquitta and M. Caffrey (2007) High-throughput automated system for crystallizing membrane proteins in lipidic mesophases IEEE Trans. Autom. Sci. Eng. 4: 129-140 ;
33 D. M. Rosenbaum, V. Cherezov, M. A. Hanson, S. G. Rasmussen, F. S. Thian, T. S. Kobilka, H. J. Choi, X. J. Yao, W. I. Weis, R. C. Stevens and B. K. Kobilka (2007) GPCR engineering yields high-resolution structural insights into beta2-adrenergic receptor function Science 318: 1266-73 ; PDB ID: 2RH1

Publications 2006:
32 V. Cherezov and M. Caffrey (2006) Picolitre-scale crystallization of membrane proteins Journal of Applied Crystallography 39: 604-606 ;
31 V. Cherezov, J. Clogston, M. Z. Papiz and M. Caffrey (2006) Room to move: crystallizing membrane proteins in swollen lipidic mesophases J Mol Biol 357: 1605-18 ; PDB ID: 2FKW
30 V. Cherezov, E. Yamashita, W. Liu, M. Zhalnina, W. A. Cramer and M. Caffrey (2006) In meso structure of the cobalamin transporter, BtuB, at 1.95 A resolution J Mol Biol 364: 716-34 ; PDB ID: 2GUF
29 P. Raman, V. Cherezov and M. Caffrey (2006) The Membrane Protein Data Bank Cell Mol Life Sci 63: 36-51 ;
28 S. R. Shaikh, V. Cherezov, M. Caffrey, S. P. Soni, D. LoCascio, W. Stillwell and S. R. Wassall (2006) Molecular organization of cholesterol in unsaturated phosphatidylethanolamines: X-ray diffraction and solid state 2H NMR reveal differences with phosphatidylcholines J Am Chem Soc 128: 5375-83 ;
27 D. P. Siegel, V. Cherezov, D. V. Greathouse, R. E. Koeppe, 2nd, J. A. Killian and M. Caffrey (2006) Transmembrane peptides stabilize inverted cubic phases in a biphasic length-dependent manner: implications for protein-induced membrane fusion Biophys J 90: 200-11 ;
26 S. M. Teeters-Kennedy, K. R. Rodriguez, T. M. Rogers, K. A. Zomchek, S. M. Williams, A. Sudnitsyn, L. Carter, V. Cherezov, M. Caffrey and J. V. Coe (2006) Controlling the passage of light through metal microchannels by nanocoatings of phospholipids J Phys Chem B 110: 21719-27 ;

Publications 2005:
25 V. Cherezov and M. Caffrey (2005) A simple and inexpensive nanoliter-volume dispenser for highly viscous materials used in membrane protein crystallization Journal of Applied Crystallography 38: 398-400 ;
24 V. I. Gordeliy, V. Cherezov and J. Teixeira (2005) Strength of thermal undulations of phospholipid membranes Phys Rev E Stat Nonlin Soft Matter Phys 72: 061913 ;

Publications 2004:
23 V. Cherezov, A. Peddi, L. Muthusubramaniam, Y. F. Zheng and M. Caffrey (2004) A robotic system for crystallizing membrane and soluble proteins in lipidic mesophases Acta Crystallogr D Biol Crystallogr 60: 1795-807 ;
22 L. V. Misquitta, Y. Misquitta, V. Cherezov, O. Slattery, J. M. Mohan, D. Hart, M. Zhalnina, W. A. Cramer and M. Caffrey (2004) Membrane protein crystallization in lipidic mesophases with tailored bilayers Structure 12: 2113-2124 ;
21 Y. Misquitta, V. Cherezov, F. Havas, S. Patterson, J. M. Mohan, A. J. Wells, D. J. Hart and M. Caffrey (2004) Rational design of lipid for membrane protein crystallization J Struct Biol 148: 169-75 ;
20 L. Muthusubramaniam, A. Peddi, Y. F. Zheng, V. Cherezov and M. Caffrey (2004) Automating crystallization of membrane proteins by robot with soft coordinate measuring Proc ICRA 1450-1455 ;
19 A. Peddi, Y. F. Zheng, V. Cherezov and M. Caffrey (2004) Automating the dispensing of viscous biomaterials Proc IROS 2: 1281-1286 ;
18 S. R. Wassall, M. R. Brzustowicz, S. R. Shaikh, V. Cherezov, M. Caffrey and W. Stillwell (2004) Order from disorder, corralling cholesterol with chaotic lipids. The role of polyunsaturated lipids in membrane raft formation Chem Phys Lipids 132: 79-88 ;
17 S. R. Wassall, S. R. Shaikh, M. R. Brzustowicz, V. Cherezov, R. A. Siddiqui, M. Caffrey and W. Stillwell (2004) Interaction of polyunsaturated fatty acids with cholesterol: A role in lipid raft phase separation Macromol. Symp. 219: 73-83 ;

Publications 2003:
16 V. Cherezov and M. Caffrey (2003) Nano-volume plates with excellent optical properties for fast, inexpensive crystallization screening of membrane proteins. J Appl Cryst 36: 1372-1377 ;
15 V. Cherezov, D. P. Siegel, W. Shaw, S. W. Burgess and M. Caffrey (2003) The kinetics of non-lamellar phase formation in DOPE-Me: relevance to biomembrane fusion J Membr Biol 195: 165-82 ;
14 S. R. Shaikh, V. Cherezov, M. Caffrey, W. Stillwell and S. R. Wassall (2003) Interaction of cholesterol with a docosahexaenoic acid-containing phosphatidylethanolamine: trigger for microdomain/raft formation? Biochemistry 42: 12028-37 ;

Publications 2002:
13 M. R. Brzustowicz, V. Cherezov, M. Caffrey, W. Stillwell and S. R. Wassall (2002) Molecular organization of cholesterol in polyunsaturated membranes: microdomain formation Biophys J 82: 285-98 ;
12 M. R. Brzustowicz, V. Cherezov, M. Zerouga, M. Caffrey, W. Stillwell and S. R. Wassall (2002) Controlling membrane cholesterol content. A role for polyunsaturated (docosahexaenoate) phospholipids Biochemistry 41: 12509-19 ;
11 V. Cherezov, J. Clogston, Y. Misquitta, W. Abdel-Gawad and M. Caffrey (2002) Membrane protein crystallization in meso: lipid type-tailoring of the cubic phase Biophys J 83: 3393-407 ;
10 V. Cherezov, H. Qiu, V. Pector, M. Vandenbranden, J. M. Ruysschaert and M. Caffrey (2002) Biophysical and transfection studies of the diC(14)-amidine/DNA complex Biophys J 82: 3105-17 ;
9 V. Cherezov, K. M. Riedl and M. Caffrey (2002) Too hot to handle? Synchrotron X-ray damage of lipid membranes and mesophases J Synchrotron Radiat 9: 333-41 ;

Publications 2001:
8 P. Balgavy, N. Kucerka, V. I. Gordeliy and V. G. Cherezov (2001) Evaluation of small-angle neutron scattering curves of unilamellar phosphatidylcholine liposomes using a multishell model of bilayer neutron scattering length density Acta Phys. Slovaca 51: 53-68 ;
7 V. Cherezov, H. Fersi and M. Caffrey (2001) Crystallization screens: compatibility with the lipidic cubic phase for in meso crystallization of membrane proteins Biophys J 81: 225-42 ;

Publications 2000:
6 V. Cherezov, A. Cheng, J. M. Petit, O. Diat and M. Caffrey (2000) Biophysics and synchrotron radiation where the marriage fails. X-ray damage of lipid membranes and mesophases Cell Mol Biol (Noisy-le-grand) 46: 1133-45 ;

Publications 1996:
5 V. I. Gordeliy, V. G. Cherezov, A. V. Anikin, M. V. Anikin, V. V. Chupin and J. Teixeira (1996) Evidence of entropic contribution to hydration forces between membranes Prog Colloid Polym Sci 100: 338-344 ;
4 V. I. Gordeliy, V. G. Cherezov and J. Teixeira (1996) Evidence of entropic contribution to "hydration" forces between membranes. Part II. Temperature dependence of the "hydration" force: a small angle neutron scattering study J Mol Struct 383: 117-124 ;
3 V. I. Gordeliy, V. G. Cherezov, A. D. Tugan-Baranovskaya and L. S. Yagujinskiy (1996) Investigation of the structure of thylakoid membranes (spinach) by means of small-angle neutron scattering Biochem Mol Biol Int 38: 485-491 ;
2 G. Klose, A. Islamov, B. Koenig and V. Cherezov (1996) Structure of Mixed Multilayers of Palmitoyloleoylphosphatidylcholine and Oligo(oxyethylene glycol) Monododecyl Ether Determined by X-ray and Neutron Diffraction Langmuir 12: 409-15 ;

Publications 1993:
1 D. Uhrikova, V. Cherezov, S. Yaradaikin and P. Balgavy (1993) Mathematical model of the cut-off effect in the homologous series of tertiary amine local anesthetics Pharmazie 48: 446-50 ;

CONTACT US: USC | Cherezov Lab | cherezov@usc.edu