Publications:

2026:

  1. Liu Y, Lee KY, He Y, Kim D, Chang H, Cherezov V, Feigon J, Qin PZ (2026) Cryo-EM structure of a 95-base-pair double-stranded DNA minicircle at 5.3 Å resolution. Nucleic Acids Res. 54(17): gkag885.

    PDB ID: 13GQ

  2. Xia M, Raskovalov A, Nguyen MVT, Mei S, Kim D, Salve J, Katritch V, Cherezov V, Zhang H (2026) Molecular mechanisms for subtype selectivity of kinin receptors’ antagonists. Nat Commun 17: 6783

    PDB ID: 9LFA, 9LFC, 9LFD

  3. Maslov I, Borshchevskiy, Perez I, Cherezov V, Hofkens J, Hendrix J, Borsch M, Gensch T (2026) ABEL-FRET bridges the timescale gap in single-molecule measurements of the structural dynamics in the A2A adenosine receptor. Comm Chem 9: 114

2025:

  1. Davoudinasab B, Raskovalov A, Lee W, Kim D, Kim H, Lam JH, Han GW, Katritch V, Cherezov V (2025) Structural insights into the mechanism of activation and inhibition of the prostaglandin D2 receptor 1. Nat Commun 16: 8944

    PDB ID: 9EI5, 9EE5, 9EKH, 9AU0, 9E9S,

  2. Wang GL, Jiang Y, Sun Y, Nasertorabi F, Weller JA, Mitra R, Batyuk A, Aparicio OM, Cherezov V, Rohs R (2025) Novel fold and wing structure of Forkhead transcription factor facilitate DNA binding. Nucleic Acids Res 53: gkaf946

    PDB ID: 9EFW

  3. Dashevskii D, Luginina A, Maslov I, Shevelyova M, Khorn P, Dmitrieva D, Kapranov I, Belousov A, Permyakov S, Cherezov V, Borshchevskiy V, Mishin A (2025) Unlocking GPCR-ligand interactions: measuring binding affinities with thermal shift assay. Prot Sci 34: e70120

  4. Chang H, Li X, Shen L, Ge X, Hao S, Wu L, Liu S, Liu J, Cherezov V, Hua T (2025) Structure basis of ligand recognition and activation of GPR55. Cell Res 35: 80-83

    PDB ID: 9IYA, 9IY8

2024:

  1. Barekatain M, Johansson LC, Lam JH, Chang H, Sadybekov AV, Han GW, Russo J, Bliesath J, Brice NL, Carlton MBL, Saikatendu KS, Sun H, Murphy ST, Monenschein H, Schiffer HH, Popov P, Lutomski CA, Robinson CV, Liu Z-J, Hua T, Katritch V, Cherezov V (2024) Structural insights into the high basal activity and inverse agonism of the orphan receptor GPR6 implicated in Parkinson's disease. Sci Signal 17: eado8741;

    PDB ID: 8T1V, 8T1W, 8TF5, 8TYW

  2. Kao G, Zhang X-N, Nasertorabi F, Katz BB, Li Z, Dai Z, Zhang Z, Zhang L, Louie SG, Cherezov V, Zhang Y (2024) Nicotinamide riboside and CD38: covalent inhibition and live-cell labeling. JACS Au 4: 4345-4360;

    PDB ID: 8VAU

  3. Chang H, Li X, Shen L, Ge X, Hao S, Wu L, Liu S, Liu J, Cherezov V, Hua T (2024) Structure basis of ligand recognition and activation of GPR55. Cell Res Published Online: 31 October 2024;

    PDB ID: 9IY8, 9IYA

  4. Kim D, Liu W, Viner R, Cherezov V (2024) Native mass spectrometry prescreening of G protein-coupled receptor complexes for cryo-EM structure determination. Structure 32: 2206-2219.e4;

    PDB ID: 8VHF

  5. Barekatain M, Liu Y, Archambeau A, Cherezov V, Fraser S, White KL, Hayes MA (2024) Insulator-based dielectrophoresis-assisted separation of insulin secretory vesicles. eLife 13: e74989;

  6. Belousov A, Maslov I, Orekhov P, Khorn P, Kuzmichev P, Baleeva N, Motov V, Bogorodskiy A, Krasnova S, Mineev K, Zinchenko D, Zernii E, Ivanovich V, Permyakov S, Hofkens J, Hendrix J, Cherezov V, Gensch T, Baranov M, Mishin A, Borshchevskiy V (2024) Monitoring GPCR conformation with GFP-inspired dyes.iScience 27: 110466;

  7. Raskovalov A, Kim D, Cherezov V (2024) One-Go: Direct detection of context-dependent GPCR activity. Cell Res 34: 543-544;

2023:

  1. Luginina A, Maslov I, Khorn P, Volkov O, Khnykin A, Kuzmichev P, Shevtsov M, Belousov A, Kapranov I, Dashevskii D, Kornilov D, Bestsennaia E, Hofkens J, Hendrix J, Gensch T, Cherezov V, Ivanovich V, Mishin A, Borshchevskiy V (2023) Functional GPCR expression in eukaryotic LEXSY system. J Mol Biol 435: 168310;

  2. Luginina A, Gusach A, Lyapina E, Khorn P, Safronova N, Shevtsov M, Dmitrieva D, Dashevskii D, Kotova T, Smirnova E, Borshchevskiy, Cherezov V, Mishin A (2023) Structural diversity of leukotriene G protein coupled receptors. J Biol Chem 299: 105247;

  3. Zhang D, Liu Y, Zaidi SA, Xu L, Zhan Y, Chen A, Guo J, Huang X-P, Roth BL, Katritch V, Cherezov V, Zhang H (2023) Structural insights into angiotensin receptor signaling modulation by balanced and biased agonists. EMBO J : e112940;

    PDB ID: 7F6G

  4. Lin X, Jiang S, Wu Y, Wei X, Han GW, Wu L, Liu J, Chen B, Zhang Z, Zhao S, Cherezov V, Xu F (2023) The activation mechanism and antibody binding mode for orphan GPR20. Cell Discov 9: 23;

    PDB ID: 8HS2, 8HS3, 8HSC

  5. Maslov I, Volkov O, Khorn P, Orekhov P, Gusach A, Kuzmichev P, Gerasimov A, Luginina A, Coucke Q, Bogorodskiy A, Gordeliy V, Wanninger S, Barth A, Mishin A, Hofkens J, Cherezov V, Gensch T, Hendrix J, Borschevskiy V (2023) Sub-millisecond conformational dynamics of the A2A adenosine receptor revealed by single-molecule FRET. Commun Biol 6: 362;

2022:

  1. Shiriaeva A, Park D, Kim G, Lee Y, Hou X, Jarhad DB, Kim G, Yu J, Hyun YE, Kim W, Gao Z-G, Jacobson KA, Han GW, Stevens RC, Jeong LS, Choi S, Cherezov V (2022) GPCR agonist-to-antagonist conversion: enabling the design of nucleoside functional switches for the A2A adenosine receptor. J Med Chem 65: 11648-11657;

    PDB ID: 8CU6, 8CU7

  2. Lyapina E, Marin E, Gusach A, Orekhov P, Gerasimov A, Luginina A, Vakhrameev D, Ergasheva M, Kovaleva M, Khusainov G, Khorn P, Shevtsov M, Kovalev K, Bukhdruker S, Okhrimenko I, Popov P, Hu H, Weierstall U, Liu W, Cho Y, Gushchin I, Rogachev A, Bourenkov G, Park S, Park G, Hyun HJ, Park J, Gordeliy V, Borshchevskiy V, Mishin A, Cherezov V (2022) Structural basis for receptor selectivity and inverse agonism in S1P5 receptors. Nat Comm 13: 4736;

    PDB ID: 7YXA

  3. Barends TRM, Stauch B, Cherezov V, Schlichting I (2022) Serial femtosecond crystallography. Nat Rev Methods Primers 2: 59;

  4. Perryman R, Renziehausen A, Shaye H, Kostagianny AD, Tsiailanis AD, Thorne T, Chatziathanasiadou MV, Sivolapenko GB, El Mubarak MA, Han GW, Zazycka, Katritch V, Lebon G, Lo Nigro C, Lattanzio L, Morse SV, Choi JJ, O'Neill K, Kanaki Z, Klinakis A, Crook T, Cherezov V, Tzakos AG, Syed N. (2022) Inhibition of the angiotensin II type 2 receptor AT2R is a novel therapeutic strategy for glioblastoma. Proc Natl Acad Sci USA 119: e2116289119;

    PDB ID: 7JNI

  5. Bolteau R, Duroux R, Laversin A, Vreulz B, Shiriaeva A, Stauch B, Han GW, Cherezov V, Renault N, Barczyk A, Ravez S, Coevoet M, Melnyk P, Liberelle M, Yous S (2022) High ligand efficiency quinazoline compounds as novel A2A adenosine receptor antagonists. Eur J Med Chem 241: 114620;

    PDB ID: 8DU3

  6. Kovalev K, Astashkin R, Gordeliy V, Cherezov V (2022) Crystallization of microbial rhodopsins. Methods Mol Biol 2501: 125-146;

  7. Motiwala Z, Aduri NG, Shaye H, Han GW, Lam JH, Katritch V, Cherezov V, Gati C (2022) Structural basis of GABA reuptake inhibition. Nature 606: 820-826;

    PDB ID: 7SK2

2021:

  1. Martynowycz MW, Shiriaeva A, Ge X, Hattne J, Nannenga BL, Cherezov V, Gonen T (2021) MicroED structure of the human adenosine receptor determined from a single nanocrystal in LCP. Proc Natl Acad Sci USA 118: e2106041118;

    PDB ID: 7RM5

  2. Liu H, Deepak RNVK, Shiriaeva A, Gati C, Batyuk A, Hu H, Weierstall U, Liu W, Wang L, Cherezov V, Fan H, Zhang C (2021) Molecular basis for lipid recognition by the prostaglandin D2 receptor CRTH2. Proc Natl Acad Sci USA 118: e2102813118;

    PDB ID: 7M8W

  3. Zhang H, Luginina A, Mishin A, Baidya M, Shukla AK, Cherezov V (2021) Structural insights into ligand recognition and activation of angiotensin receptors. Trends Pharmacol Sci 42: 577-587;

  4. Michaelian N, Sadybekov A, Besserer-Offroy É, Han GW, Krishnamurthy H, Zamlynny BA, Fradera X, Siliphaivanh P, Presland J, Spencer KB, Soisson SM, Popov P, Sarret P, Katritch V, Cherezov V (2021) Structural insights on ligand recognition at the human leukotriene B4 receptor 1. Nat Commun 12: 2971;

    PDB ID: 7K15

  5. Shaye H, Stauch B, Gati C, Cherezov V (2021) Molecular mechanisms of metabotropic GABAB receptor function. Sci Adv 7: eabg3362;

  6. Lemel L, Nieścierowicz K, García-Fernández MD, Darré L, Durroux T, Busnelli M, Pezet M, Rebeille F, Jouhet J, Mouillac B, Domene C, Chini B, Cherezov V, Moreau CJ (2021) The ligand-bound state of a G protein-coupled receptor stabilizes the interaction of functional cholesterol molecules.J Lipid Res 62: 100059;

2020:

  1. Sadybekov AA, Brouillette RL, Marin E, Sadybekov AV, Luginina A, Gusach A, Mishin A, Besserer-Offroy É, Longpré J-M, Borshchevskiy V, Cherezov V, Sarret P, Katritch V (2020) Structure-Based Virtual Screening of Ultra-Large Library Yields Potent Antagonists for a Lipid GPCR. Biomolecules 10: 1634;

  2. Marin E, Luginina A, Gusach A, Kovalev K, Bukhdruker S, Khorn P, Polovinkin V, Lyapina E, Rogachev A, Gordeliy V, Mishin A, Cherezov V, Borshchevskiy V (2020) Small-wedge synchrotron and serial XFEL datasets for Cysteinyl leukotriene GPCRs. Sci Data 7: 388;

  3. Lee M-Y, Geiger J, Ishchenko A, Han GW, Barty A, White TA, Gati C, Batyuk A, Hunter MS, Aquila A, Boutet S, Weierstall U, Cherezov V, Liu W (2020) Harnessing the power of an X-ray laser for serial crystallography of membrane proteins crystallized in lipidic cubic phase. IUCrJ 7: 976-984;

    PDB ID: 6WQA

  4. Vrettos EI, Valverde IE, Mascarin A, Pallier PN, Cerofolini L, Fragai M, Parigi G, Hirmiz B, Bekas N, Grob NM, Stylos EK, Shaye H, Borgo MD, Aguilar MI, Magnani F, Syed N, Crook T, Waqif E, Ghazaly E, Cherezov V, Widdop RE, Luchinat C, Michael-Titus AT, Mindt TL, Tzakos AG (2020) Single peptide backbone surrogate mutations to regulate angiotensin GPCR subtype selectivity. Chemistry 26: 10690-10694;

  5. Shaye H, Ishchenko A, Lam JH, Han GW, Xue L, Rondard P, Pin J-P, Katritch V, Gati C, Cherezov V (2020) Structural basis of the activation of a metabotropic GABA receptor. Nature 584: 298-303;

    PDB ID: 6UO8, 6UO9, 6UOA, 6VJM

  6. Gusach A, Maslov I, Luginina A, Borshchevskiy V, Mishin A, Cherezov V (2020) Beyond structure: emerging approaches to study GPCR dynamics. Curr Opin Struct Biol 63: 18-25;

  7. Zook J, Shekhar M, Hansen D, Conrad C, Grant T, Gupta C, White T, Barty A, Basu S, Zhao Y, Zatsepin N, Ishchenko A, Batyuk A, Gati C, Li C, Galli L, Coe J, Hunter M, Liang M, Weierstall U, Nelson G, James D, Stauch B, Craciunescu F, Thifault D, Liu W, Cherezov V, Singharoy A, Fromme P (2020) XFEL and NMR structures of Francisella lipoprotein reveal conformational space of drug target against tularemia. Structure 28: 540-547;

    PDB ID: 6PNY

  8. Kuklin A, Zabelskii D, Gordeliy I, Teixeira J, Brûlet A, Chupin V, Cherezov V, Gordeliy V (2020) On the origin of the anomalous behavior of lipid membrane properties in the vicinity of the chain-melting phase transition. Sci Rep 10: 5749;

  9. Stauch B, Johansson LC, Cherezov V (2020) Structural insights into melatonin receptors.FEBS J 287: 1496-1510;

  10. Stein RM, Kang HJ, McCorvy JD, Glatfelter GC, Jones AJ, Che T, Slocum S, Huang X-P, Savych O, Moroz YS, Stauch B, Johansson LC, Cherezov V, Kenakin T, Irwin JJ, Shoichet BK, Roth BL, Dubocovich ML (2020) Virtual discovery of melatonin receptor ligands to modulate circadian rhythms. Nature 579: 609-614;

2019:

  1. Gusach A, Luginina A, Marin E, Brouillette R, Besserer-Offroy E, Longpre JM, Ishchenko A, Popov P, Patel N, Fujimoto T, Maruyama T, Stauch B, Ergasheva M, Romanovskaia D, Stepko A, Kovalev K, Shevtsov M, Gordeliy V, Han GW, Katritch V, Borshchevskiy V, Sarret P, Mishin A, Cherezov V (2019) Structural basis of ligand selectivity and disease mutations in cysteinyl leukotriene receptors. Nat Commun 10: 5573;

    PDB ID: 6RZ6, 6RZ7, 6RZ8, 6RZ9,

  2. Ishchenko A, Stauch B, Han GW, Batyuk A, Shiriaeva A, Li C, Zatsepin N, Weierstall U, Liu W, Nango E, Nakane T, Tanaka R, Tono K, Joti Y, Iwata S, Moraes I, Gati C, Cherezov V (2019) Toward G protein-coupled receptor structure-based drug design using X-ray lasers. IUCrJ 6: 1106-1119;

    PDB ID: 6PRZ, 6PS0, 6PS1, 6PS2, 6PS3, 6PS4, 6PS5, 6PS6, 6PS7, 6PS8

  3. Luginina A, Gusach A, Marin E, Mishin A, Brouillette R, Popov P, Shiriaeva A, Besserer-Offroy E, Longpre JM, Lyapina E, Ishchenko A, Patel N, Polovinkin V, Safronova N, Bogorodskiy A, Edelweiss E, Hu H, Weierstall U, Liu W, Batyuk A, Gordeliy V, Han GW, Sarret P, Katritch V, Borshchevskiy V, Cherezov V (2019) Structure-based mechanism of cysteinyl leukotriene receptor inhibition by antiasthmatic drugs. Sci Adv 5: eaax2518;

    PDB ID: 6RZ4, 6RZ5,

  4. Mishin A, Gusach A, Luginina A, Marin E, Borshchevskiy V, Cherezov V (2019) An outlook on using serial femtosecond crystallography in drug discovery. Expert Opin Drug Discov 14: 933-945;

  5. Zhang Q, Cherezov V (2019) Chemical tools for membrane protein structural biology. Curr Opin Struct Biol 58: 278-285;

  6. Johansson LC, Stauch B, McCorvy JD, Han GW, Patel N, Huang X-P, Batyuk A, Gati C, Slocum ST, Li C, Grandner JM, Hao S, Olsen RHJ, Tribo AR, Zaare S, Zhu L, Zatsepin NA, Weierstall U, Yous S, Stevens RC, Liu W, Roth BL, Katritch V, Cherezov V (2019) XFEL structures of the human MT2 melatonin receptor reveal the basis of subtype selectivity. Nature 569: 289;

    PDB ID: 6ME6, PDB ID: 6ME7, PDB ID: 6ME8, PDB ID: 6ME9

  7. Stauch B, Johansson LC, McCorvy JD, Patel N, Han GW, Huang X-P, Gati C, Batyuk A, Slocum ST, Ishchenko A, Brehm W, White TA, Michaelian N, Madsen C, Zhu L, Grant TD, Grandner JM, Shiriaeva A, Olsen RHJ, Tribo AR, Yous S, Stevens RC, Weierstall U, Katritch V, Roth BL, Liu W, Cherezov V (2019) Structural basis of ligand recognition at the human MT1 melatonin receptor. Nature 569: 284;

    PDB ID: 6ME2, PDB ID: 6ME3, PDB ID: 6ME4, PDB ID: 6ME5

  8. Martin-Garcia JM, Zhu L, Mendez D, Lee M-Y, Chun E, Li C, Hu H, Subramanian G, Kissick D, Ogata C, Henning R, Ishchenko A, Dobson Z, Zhang S, Weierstall U, Spence JCH, Fromme P, Zatsepin NA, Fischetti RF, Cherezov V, Liu W (2019) High-viscosity injector-based pink-beam serial crystallography of microcrystals at a synchrotron radiation source. IUCrJ 6;

    PDB ID: 6MH6, PDB ID: 6MH8

  9. Gutierrez MG, Deyell J, White KL, Dalle Ore LC, Cherezov V, Stevens RC, Malmstadt N (2019) The lipid phase preference of the adenosine A2A receptor depends on its ligand binding state. Chem Commun 55: 5724-5727; ,

    PDB ID: 6M9T

  10. Audet M, White KL, Breton B, Zarzycka B, Han GW, Lu Y, Gati C, Batyuk A, Popov P, Velasquez J, Manahan D, Hu H, Weierstall U, Liu W, Shui W, Katritch V, Cherezov V, Hanson MA, Stevens RC (2019) Crystal structure of misoprostol bound to the labor inducer prostaglandin E2 receptor. Nat Chem Biol 15: 11-17; ,

    PDB ID: 6M9T

2018:

  1. Popov P, Peng Y, Shen L, Stevens RC, Cherezov V, Liu ZJ, Katritch V (2018) Computational design of thermostabilizing point mutations for G protein-coupled receptors. eLife 7: e34729; ,

  2. Abola EE, Weierstall U, Liu W, Cherezov V (2018) Delivery of GPCR Crystals for Serial Femtosecond Crystallography. in Protein Crystallography: Challenges and Practical Solutions Chapter 2: 28-53;

  3. Ishchenko A, Gati C, Cherezov V (2018) Structural biology of G protein-coupled receptors: new opportunities from XFELs and cryoEM. Curr Opin Struct Biol 51: 44-52; , ,

  4. Stauch B, Cherezov V (2018) Serial Femtosecond Crystallography of G Protein-Coupled Receptors. Annu Rev Biophys 47: 377-397; , ,

  5. Che T, Majumdar S, Zaidi SA, Ondachi P, McCorvy JD, Wang S, Mosier PD, Uprety R, Vardy E, Krumm BE, Han GW, Lee MY, Pardon E, Steyaert J, Huang XP, Strachan RT, Tribo AR, Pasternak GW, Carroll FI, Stevens RC, Cherezov V, Katritch V, Wacker D, Roth BL (2018) Structure of the Nanobody-Stabilized Active State of the Kappa Opioid Receptor. Cell 172: 55-67; ,

    PDB ID: 6B73

  6. Broecker J, Morizumi T, Ou WL, Klingel V, Kuo A, Kissick DJ, Ishchenko A, Lee MY, Xu S, Makarov O, Cherezov V, Ogata CM, Ernst OP (2018) High-throughput in situ X-ray screening of and data collection from protein crystals at room temperature and under cryogenic conditions. Nat Protoc 13: 260-292; ,

    PDB ID: 5VRA, PDB ID: 5WJK, PDB ID: 5WKT

2017:

  1. Johansson LC, Stauch B, Ishchenko A, Cherezov V (2017) A bright future for serial femtosecond crystallography with XFELs. Trends Biochem Sci 42: 749-762; ,

  2. Zhou XE, He Y, de Waal PW, Gao X, Kang Y, Van Eps N, Yin Y, Pal K, Goswami D, White TA, Barty A, Latorraca NR, Chapman HN, Hubbell WL, Dror RO, Stevens RC, Cherezov V, Gurevich VV, Griffin PR, Ernst OP, Melcher K, Xu HE (2017) Identification of phosphorylation codes for arrestin recruitment by G protein-coupled receptors. Cell 170: 457-469; ,

    PDB ID: 5W0P

  3. Ishchenko A, Wacker D, Kapoor M, Zhang A, Han GW, Basu S, Patel N, Messerschmidt M, Weierstall U, Liu W, Katritch V, Roth BL, Stevens RC, Cherezov V (2017) Structural insights into the extracellular recognition of the human serotonin 2B receptor by an antibody. Proc Natl Acad Sci USA 114: 8223-8228; ,

    PDB ID: 5TUD

  4. Padayatti PS, Leung JH, Mahinthichaichan P, Tajkhorshid E, Ishchenko A, Cherezov V, Soltis SM, Jackson JB, Stout CD, Gennis RB, Zhang Q (2017) Critical role of water molecules in proton translocation by the membrane-bound transhydrogenase. Structure 25: 1111-1119; ,

    PDB ID: 5UNI

  5. Zheng Y, Han GW, Abagyan R, Wu B, Stevens RC, Cherezov V, Kufareva I, Handel TM (2017) Structure of CC chemokine receptor 5 with a potent chemokine angagonist reveals mechanisms of chemokine recognition and molecular mimicry by HIV. Immunity 46: 1005-1017; ,

    PDB ID: 5UIW

  6. Zhang H, Qiao A, Yang D, Yang L, Dai A, de Graaf C, Reedtz-Runge S, Dharmarajan V, Zhang H, Han GW, Grant TD, Sierra RG, Weierstall U, Nelson G, Liu W, Wu Y, Ma L, Cai X, Lin G, Wu X, Geng Z, Dong Y, Song G, Griffin PR, Lau J, Cherezov V, Yang H, Hanson MA, Stevens RC, Zhao Q, Jiang H, Wang MW, Wu B (2017) Structure of the full-length glucagon class B G protein-coupled receptor. Nature 546: 259-264; ,

    PDB ID: 5XF1, PDB ID: 5XEZ

  7. Ishchenko A, Abola EE, Cherezov V (2017) Crystallization of membrane proteins: an overview. Methods Mol Biol 1607: 117-141; ,

  8. Ishchenko A, Peng L, Zinovev E, Vlasov A, Lee SC, Kuklin A, Mishin A, Borshchevskiy V, Zhang Q, Cherezov V (2017) Chemically stable lipids for membrane protein crystallization. Cryst Growth Des 17: 3502-3511; ,

    PDB ID: 5VN7, PDB ID: 5VN9

  9. Martin-Garcia JM, Conrad CE, Nelson G, Stander N, Zatsepin NA, Zook J, Zhu L, Geiger J, Chun E, Kissick D, Hilgart MC, Ogata C, Ishchenko A, Nagaratnam N, Roy-Chowdhury S, Coe J, Subramanian G, Schaffer A, James D, Ketwala G, Venugopalan N, Xu S, Corcoran S, Ferguson D, Weierstall U, Spence JCH, Cherezov V, Fromme P, Fischetti RF, Liu W (2017) Serial millisecond crystallography of membrane and soluble protein microcrystals using synchrotron radiation. IUCrJ 4: 439-454; ,

    PDB ID: 5UVL, PDB ID: 5UVK, PDB ID: 5UVJ, PDB ID: 5UVI

  10. Zhang X, Zhao F, Wu Y, Yang J, Han GW, Zhao S, Ishchenko A, Ye L, Lin X, Ding K, Dharmarajan V, Griffin PR, Gati C, Nelson G, Hunter MS, Hanson MA, Cherezov V, Stevens RC, Tan W, Tao H, Xu F (2017) Crystal structure of a multi-domain human smoothened receptor in complex with a super stabilizing ligand. Nat Commun 8: 15383; ,

    PDB ID: 5V56, PDB ID: 5V57

  11. Melnikov I, Polovinkin V, Kovalev K, Gushchin I, Shevtsov M, Shevchenko V, Mishin A, Alekseev A, Rodriguez-Valera F, Borshchevskiy V, Cherezov V, Leonard GA, Gordeliy V, Popov A (2017) Fast iodide-SAD phasing for high-throughput membrane protein structure determination. Sci Adv 3: e1602952; ,

    PDB ID: 5JTB, PDB ID: 5JSI, PDB ID: 5JRF, PDB ID: 5JGP

  12. Zhang H, Han GW, Batyuk A, Ishchenko A, White KL, Patel N, Sadybekov A, Zamlynny B, Rudd MT, Hollenstein K, Tolstikova A, White TA, Hunter MS, Weierstall U, Liu W, Babaoglu K, Moore EL, Katz RD, Shipman JM, Garcia-Calvo M, Sharma S, Sheth P, Soisson SM, Stevens RC, Katritch V, Cherezov V (2017) Structural basis for selectivity and diversity in angiotensin II receptors. Nature 544: 327-332; ,

    PDB ID: 5UNH, PDB ID: 5UNG, PDB ID: 5UNF

2016:

  1. Zheng Y, Qin L, Zacarías NV, de Vries H, Han GW, Gustavsson M, Dabros M, Zhao C, Cherney RJ, Carter P, Stamos D, Abagyan R, Cherezov V, Stevens RC, IJzerman AP, Heitman LH, Tebben A, Kufareva I, Handel TM (2016) Structure of CC chemokine receptor 2 with orthosteric and allosteric antagonists. Nature 540: 458-461; ,

    PDB ID: 5T1A

  2. Batyuk A, Galli L, Ishchenko A, Han GW, Gati C, Popov PA, Lee MY, Stauch B, White TA, Barty A, Aquila A, Hunter MS, Liang M, Boutet S, Pu M, Liu ZJ, Nelson G, James D, Li C, Zhao Y, Spence JC, Liu W, Fromme P, Katritch V, Weierstall U, Stevens RC, Cherezov V (2016) Native phasing of X-ray free-electron laser data for a G protein-coupled receptor. Sci Adv 2: e1600292; ,

    PDB ID: 5K2A, PDB ID: 5K2B, PDB ID: 5K2C, PDB ID: 5K2D

  3. Ishchenko A, Cherezov V, Liu W (2016) Preparation and delivery of protein microcrystals in lipidic cubic phase for serial femtosecond crystallography. J Vis Exp 115: e54463; ,

  4. Zhu L, Weierstall U, Cherezov V, Liu W (2016) Serial femtosecond crystallography of membrane proteins, in The Next Generation in Membrane Protein Structure Determination. I. Moraes, Editor. Adv Exp Med Biol 922: 151-160;

  5. White TA, Barty A, Liu W, Ishchenko A, Zhang H, Gati C, Zatsepin NA, Basu S, Oberthür D, Metz M, Beyerlein KR, Yoon CH, Yefanov OM, James D, Wang D, Messerschmidt M, Koglin JE, Boutet S, Weierstall U, Cherezov V (2016) Serial femtosecond crystallography datasets from G protein-coupled receptors. Sci Data 3: 160057; ,

  6. Zhou XE, Gao X, Barty A, Kang Y, He Y, Liu W, Ishchenko A, White TA, Yefanov O, Han GW, Xu Q, de Waal PW, Suino-Powell KM, Boutet S, Williams GJ, Wang M, Li D, Caffrey M, Chapman HN, Spence JC, Fromme P, Weierstall U, Stevens RC, Cherezov V, Melcher K, Xu HE (2016) X-ray laser diffraction for structure determination of the rhodopsin-arrestin complex. Sci Data 3: 160021; ,

    PDB ID: 5DGY

  7. Heifetz A, Chudyk EI, Gleave L, Aldeghi M, Cherezov V, Fedorov DG, Biggin PC, Bodkin MJ (2016) The Fragment Molecular Orbital Method Reveals New Insight into the Chemical Nature of GPCR-Ligand Interactions. J Chem Inf Model 56: 159-172; ,

2015:

  1. Li D, Stansfeld PJ, Sansom MSP, Keogh A, Vogeley L, Howe N, Lyons JA, Aragao D, Fromme P, Fromme R, Basu S, Grotjohann I, Kupitz C, Rendek K, Weierstall U, Zatsepin NA, Cherezov V, Liu W, Bandaru S, English NJ, Gati C, Barty A, Yefanov O, Chapman HN, Diederichs K, Messerschmidt M, Boutet S, Williams GJ, Marvin Seibert M, Caffrey M (2015) Ternary structure reveals mechanism of a membrane diacylglycerol kinase. Nat Commun 6: 10140; ,

    PDB ID: 4UXX, PDB ID: 4UXW, PDB ID: 4UYO, PDB ID: 4UXZ

  2. Bogorodskiy A, Frolov F, Mishin A, Round E, Polovinkin V, Cherezov V, Gordeliy V, Bueldt G, Gensch T, Borshchevskiy V (2015) Nucleation and Growth of Membrane Protein Crystals in Meso - a Fluorescence Microscopy Study. Cryst Growth Des 15: 5656-5660;

  3. Zhang H, Unal H, Desnoyer R, Han GW, Patel N, Katritch V, Karnik SS, Cherezov V, Stevens RC (2015) Structural Basis for Ligand Recognition and Functional Selectivity at Angiotensin Receptor. J Biol Chem 290: 29127-29139; ,

    PDB ID: 4ZUD

  4. Miller RL, Thompson AA, Trapella C, Guerrini R, Malfacini D, Patel N, Han GW, Cherezov V, Caló G, Katritch V, Stevens RC (2015) The Importance of Ligand-Receptor Conformational Pairs in Stabilization: Spotlight on the N/OFQ G Protein-Coupled Receptor. Structure 23: 2291-2299; ,

    PDB ID: 5DHH, PDB ID: 5DHG

  5. Lawrence RM, Conrad CE, Zatsepin NA, Grant TD, Liu H, James D, Nelson G, Subramanian G, Aquila A, Hunter MS, Liang M, Boutet S, Coe J, Spence JCH, Weierstall U, Liu W, Fromme P, Cherezov V, Hogue BG (2015) Serial femtosecond X-ray diffraction of enveloped virus microcrystals. Struct Dyn 2: 041720;

  6. Fromme R, Ishchenko A, Metz M, Chowdhury SR, Basu S, Boutet S, Fromme P, White TA, Barty A, Spence JC, Weierstall U, Liu W, Cherezov V (2015) Serial femtosecond crystallography of soluble proteins in lipidic cubic phase. IUCrJ 2: 541-551; ,

    PDB ID: 4ZIX, PDB ID: 4ZIZ

  7. Kang Y, Zhou XE, Gao X, He Y, Liu W, Ishchenko A, Barty A, White TA, Yefanov O, Han GW, Xu Q, de Waal PW, Ke J, Tan MH, Zhang C, Moeller A, West GM, Pascal BD, Van Eps N, Caro LN, Vishnivetskiy SA, Lee RJ, Suino-Powell KM, Gu X, Pal K, Ma J, Zhi X, Boutet S, Williams GJ, Messerschmidt M, Gati C, Zatsepin NA, Wang D, James D, Basu S, Roy-Chowdhury S, Conrad CE, Coe J, Liu H, Lisova S, Kupitz C, Grotjohann I, Fromme R, Jiang Y, Tan M, Yang H, Li J, Wang M, Zheng Z, Li D, Howe N, Zhao Y, Standfuss J, Diederichs K, Dong Y, Potter CS, Carragher B, Caffrey M, Jiang H, Chapman HN, Spence JC, Fromme P, Weierstall U, Ernst OP, Katritch V, Gurevich VV, Griffin PR, Hubbell WL, Stevens RC, Cherezov V, Melcher K, Xu HE (2015) Crystal structure of rhodopsin bound to arrestin by femtosecond X-ray laser. Nature 523: 561-567; ,

    PDB ID: 4ZWJ

  8. Conrad CE, Basu S, James D, Wang D, Schaffer A, Roy-Chowdhury S, Zatsepin NA, Aquila A, Coe J, Gati C, Hunter MS, Koglin JE, Kupitz C, Nelson G, Subramanian G, White TA, Zhao Y, Zook J, Boutet S, Cherezov V, Spence JC, Fromme R, Weierstall U, Fromme P (2015) A novel inert crystal delivery medium for serial femtosecond crystallography. IUCrJ 2: 421-430; ,

    PDB ID: 4Z8K

  9. Zhang H, Unal H, Gati C, Han GW, Liu W, Zatsepin NA, James D, Wang D, Nelson G, Weierstall U, Sawaya MR, Xu Q, Messerschmidt M, Williams GJ, Boutet S, Yefanov OM, White TA, Wang C, Ishchenko A, Tirupula KC, Desnoyer R, Coe J, Conrad CE, Fromme P, Stevens RC, Katritch V, Karnik SS, Cherezov V (2015) Structure of the Angiotensin Receptor Revealed by Serial Femtosecond Crystallography. Cell 161: 833-844; ,

    PDB ID: 4YAY

  10. Heifetz A, Schertler GF, Seifert R, Tate CG, Sexton PM, Gurevich VV, Fourmy D, Cherezov V, Marshall FH, Storer RI, Moraes I, Tikhonova IG, Tautermann CS, Hunt P, Ceska T, Hodgson S, Bodkin MJ, Singh S, Law RJ, Biggin PC (2015) GPCR structure, function, drug discovery and crystallography: report from Academia-Industry International Conference (UK Royal Society) Chicheley Hall, 1-2 September 2014. Naunyn-Schmiedeberg's Arch Pharmacol 388: 883-903; ,

    PDB ID: 4YAY

  11. Fenalti G, Abola EE, Wang C, Wu B, Cherezov V (2015) Fluorescence recovery after photobleaching in Lipidic Cubic Phase (LCP-FRAP): a precrystallization assay for membrane proteins. Met Enzymol 557: 417-437; ,

  12. Zhang D, Gao ZG, Zhang K, Kiselev E, Crane S, Wang J, Paoletta S, Yi C, Ma L, Zhang W, Han GW, Liu H, Cherezov V, Katritch V, Jiang H, Stevens RC, Jacobson KA, Zhao Q, Wu B (2015) Two disparate ligand-binding sites in the human P2Y1 receptor. Nature 520: 317-321; ,

    PDB ID: 4XNV, PDB ID: 4XNW

  13. Fenalti G, Zatsepin NA, Betti C, Giguere P, Han GW, Ishchenko A, Liu W, Guillemyn K, Zhang H, James D, Wang D, Weierstall U, Spence JC, Boutet S, Messerschmidt M, Williams GJ, Gati C, Yefanov OM, White TA, Oberthuer D, Metz M, Yoon CH, Barty A, Chapman HN, Basu S, Coe J, Conrad CE, Fromme R, Fromme P, Tourwé D, Schiller PW, Roth BL, Ballet S, Katritch V, Stevens RC, Cherezov V (2015) Structural basis for bifunctional peptide recognition at human δ-opioid receptor. Nat Struct Mol Biol 22: 265-268; ,

    PDB ID: 4RWA, PDB ID: 4RWD

  14. Qin L, Kufareva I, Holden LG, Wang C, Zheng Y, Zhao C, Fenalti G, Wu H, Han GW, Cherezov V, Abagyan R, Stevens RC, Handel TM (2015) Crystal structure of the chemokine receptor CXCR4 in complex with a viral chemokine. Science 347: 1117-1122; ,

    PDB ID: 4RWS

  15. Nogly P, James D, Wang D, White TA, Zatsepin N, Shilova A, Nelson G, Liu H, Johansson L, Heymann M, Jaeger K, Metz M, Wickstrand C, Wu W, Båth P, Berntsen P, Oberthuer D, Panneels V, Cherezov V, Chapman H, Schertler G, Neutze R, Spence J, Moraes I, Burghammer M, Standfuss J, Weierstall U (2015) Lipidic cubic phase serial millisecond crystallography using synchrotron radiation. IUCrJ 2: 168-176; ,

    PDB ID: 4X31, PDB ID: 4X32

  16. Isberg V, de Graaf C, Bortolato A, Cherezov V, Katritch V, Marshall FH, Mordalski S, Pin JP, Stevens RC, Vriend G, Gloriam DE (2015) Generic GPCR residue numbers - aligning topology maps while minding the gaps. Trends Pharmacol Sci 36: 22-31; ,

2014:

  1. Gater DL, Saurel O, Iordanov I, Liu W, Cherezov V, Milon A (2014) Two classes of cholesterol binding sites for the β2AR revealed by thermostability and NMR. Biophysics J 107: 2305-2312; ,

  2. Goren MA, Morizumi T, Menon I, Joseph JS, Dittman JS, Cherezov V, Stevens RC, Ernst OP, Menon AK (2014) Constitutive phospholipid scramblase activity of a G protein-coupled receptor. Nat Commun 5: 5115; ,

  3. Liu W, Ishchenko A, Cherezov V (2014) Preparation of microcrystals in lipidic cubic phase for serial femtosecond crystallography. Nat Protoc 9: 2123-2134; ,

  4. Wang C, Wu H, Evron T, Vardy E, Han GW, Huang XP, Hufeisen SJ, Mangano TJ, Urban DJ, Katritch V, Cherezov V, Caron MG, Roth BL, Stevens RC (2014) Structural basis for Smoothened receptor modulation and chemoresistance to anticancer drugs. Nat Commun 5: 4355; ,

    PDB ID: 4N4W, PDB ID: 4QIN, PDB ID: 4QIM

  5. Liu W, Wacker D, Wang C, Abola E, Cherezov V (2014) Femtosecond crystallography of membrane proteins in the lipidic cubic phase. Phil Trans R Soc B 369: 20130314; ,

  6. Ishchenko A, Abola E, Cherezov V (2014) Lipidic Cubic Phase Technologies for Structural Studies of Membrane Proteins. in Membrane Protein Production for Structural Analysis, ed. I. Mus-Veteau, pages 289-314 (Springer);

  7. Zhang J, Zhang K, Gao ZG, Paoletta S, Zhang D, Han GW, Li T, Ma L, Zhang W, Müller CE, Yang H, Jiang H, Cherezov V, Katritch V, Jacobson KA, Stevens RC, Wu B, Zhao Q (2014) Agonist-bound structure of the human P2Y12 receptor. Nature 509: 119-122; ,

    PDB ID: 4PXZ, PDB ID: 4PY0

  8. Zhang K, Zhang J, Gao ZG, Zhang D, Zhu L, Han GW, Moss SM, Paoletta S, Kiselev E, Lu W, Fenalti G, Zhang W, Müller CE, Yang H, Jiang H, Cherezov V, Katritch V, Jacobson KA, Stevens RC, Wu B, Zhao Q (2014) Structure of the human P2Y12 receptor in complex with an antithrombotic drug. Nature 509: 115-118; ,

    PDB ID: 4NTJ

  9. Katritch V, Fenalti G, Abola EE, Roth BL, Cherezov V, Stevens RC (2014) Allosteric sodium in class A GPCR signaling. Trends Biochem Sci 39: 233-244; ,

  10. Wu H, Wang C, Gregory KJ, Han GW, Cho HP, Xia Y, Niswender CM, Katritch V, Meiler J, Cherezov V, Conn PJ, Stevens RC (2014) Structure of a class C GPCR metabotropic glutamate receptor 1 bound to an allosteric modulator. Science 344: 58-64; ,

    PDB ID: 4OR2

  11. Weierstall U, James D, Wang C, White TA, Wang D, Liu W, Spence JC, Bruce Doak R, Nelson G, Fromme P, Fromme R, Grotjohann I, Kupitz C, Zatsepin NA, Liu H, Basu S, Wacker D, Han GW, Katritch V, Boutet S, Messerschmidt M, Williams GJ, Koglin JE, Marvin Seibert M, Klinker M, Gati C, Shoeman RL, Barty A, Chapman HN, Kirian RA, Beyerlein KR, Stevens RC, Li D, Shah ST, Howe N, Caffrey M, Cherezov V (2014) Lipidic cubic phase injector facilitates membrane protein serial femtosecond crystallography. Nat Commun 5: 3309; ,

    PDB ID: 4O9R

  12. Fenalti G, Giguere PM, Katritch V, Huang XP, Thompson AA, Cherezov V, Roth BL, Stevens RC (2014) Molecular control of δ-opioid receptor signalling. Nature 506: 191-196; ,

    PDB ID: 4N6H

  13. Niescierowicz K, Caro L, Cherezov V, Vivaudou M, Moreau CJ (2014) Functional assay for T4 lysozyme-engineered G protein-coupled receptors with an ion channel reporter. Structure 22: 149-155; ,

2013:

  1. Liu W, Wacker D, Gati C, Han GW, James D, Wang D, Nelson G, Weierstall U, Katritch V, Barty A, Zatsepin NA, Li D, Messerschmidt M, Boutet S, Williams GJ, Koglin JE, Seibert MM, Wang C, Shah ST, Basu S, Fromme R, Kupitz C, Rendek KN, Grotjohann I, Fromme P, Kirian RA, Beyerlein KR, White TA, Chapman HN, Caffrey M, Spence JC, Stevens RC, Cherezov V (2013) Serial femtosecond crystallography of G protein-coupled receptors. Science 342: 1521-1524; ,

    PDB ID: 4NC3

  2. Gutiérrez-de-Terán H, Massink A, Rodríguez D, Liu W, Han GW, Joseph JS, Katritch I, Heitman LH, Xia L, Ijzerman AP, Cherezov V, Katritch V, Stevens RC (2013) The role of a sodium ion binding site in the allosteric modulation of the A2A adenosine G Protein-Coupled Receptor. Structure 21: 2175-2185; ,

  3. Tan Q, Zhu Y, Li J, Chen Z, Han GW, Kufareva I, Li T, Ma L, Fenalti G, Li J, Zhang W, Xie X, Yang H, Jiang H, Cherezov V, Liu H, Stevens RC, Zhao Q, Wu B (2013) Structure of the CCR5 chemokine receptor-HIV entry inhibitor maraviroc complex. Science 341: 1387-1390; ,

    PDB ID: 4MBS

  4. Lane JR, Chubukov P, Liu W, Canals M, Cherezov V, Abagyan R, Stevens RC, Katritch V (2013) Structure-based ligand discovery targeting orthosteric and allosteric pockets of dopamine receptors. Mol Pharmacol 84: 794-807; ,

  5. Siu FY, He M, de Graaf C, Han GW, Yang D, Zhang Z, Zhou C, Xu Q, Wacker D, Joseph JS, Liu W, Lau J, Cherezov V, Katritch V, Wang MW, Stevens RC (2013) Structure of the human glucagon class B G-protein-coupled receptor. Nature 499: 444-449; ,

    PDB ID: 4L6R

  6. Madden JT, Toth SJ, Dettmar CM, Newman JA, Oglesbee RA, Hedderich HG, Everly RM, Becker M, Ronau JA, Buchanan SK, Cherezov V, Morrow ME, Xu S, Ferguson D, Makarov O, Das C, Fischetti R, Simpson GJ (2013) Integrated nonlinear optical imaging microscope for on-axis crystal detection and centering at a synchrotron beamline. J. Synchrotron Radiat. 20: 531-540; ,

  7. Gater DL, Réat V, Czaplicki G, Saurel O, Milon A, Jolibois F, Cherezov V (2013) Hydrogen Bonding of Cholesterol in the Lipidic Cubic Phase. Langmuir 29: 8031-8038; ,

  8. Wang C, Wu H, Katritch V, Han GW, Huang XP, Liu W, Siu FY, Roth BL, Cherezov V, Stevens RC (2013) Structure of the human smoothened receptor bound to an antitumour agent. Nature 497: 338-343; ,

    PDB ID: 4JKV

  9. Wacker D, Wang C, Katritch V, Han GW, Huang XP, Vardy E, McCorvy JD, Jiang Y, Chu M, Siu FY, Liu W, Xu HE, Cherezov V, Roth BL, Stevens RC (2013) Structural features for functional selectivity at serotonin receptors. Science 340: 615-619; ,

    PDB ID: 4IB4

  10. Wang C, Jiang Y, Ma J, Wu H, Wacker D, Katritch V, Han GW, Liu W, Huang XP, Vardy E, McCorvy JD, Gao X, Zhou XE, Melcher K, Zhang C, Bai F, Yang H, Yang L, Jiang H, Roth BL, Cherezov V, Stevens RC, Xu HE (2013) Structural basis for molecular recognition at serotonin receptors. Science 340: 610-614; ,

    PDB ID: 4IAR, PDB ID: 4IAQ

  11. Kissick DJ, Dettmar CM, Becker M, Mulichak AM, Cherezov V, Ginell SL, Battaile KP, Keefe LJ, Fischetti RF, Simpson GJ (2013) Towards protein-crystal centering using second-harmonic generation (SHG) microscopy. Acta Crystallogr D Biol Crystallogr 69: 843-851; ,

    PDB ID: 4DC5, PDB ID: 4DC6, PDB ID: 4DC7, PDB ID: 4DC8

  12. Stevens RC, Cherezov V, Katritch V, Abagyan R, Kuhn P, Rosen H, Wüthrich K (2013) The GPCR Network: a large-scale collaboration to determine human GPCR structure and function. Nat Rev Drug Discov 12: 25-34; ,

  13. Katritch V, Cherezov V, and Stevens RC (2013) Structure-Function of the G Protein-Coupled Receptors Superfamily. Annu Rev Pharmacol Toxicol 53: 531-556; , ,

2012:

  1. Santos JS, Asmar-Rovira GA, Han GW, Liu W, Syeda R, Cherezov V, Baker KA, Stevens RC, Montal M (2012) Crystal structure of a voltage-gated K+ channel pore module in a closed state in lipid membranes. J Biol Chem 287: 43063-43070; ,

    PDB ID: 4H33, PDB ID: 4H37

  2. Joseph JS, Abola EE, Cherezov V (2012) Structural Insights into Cholesterol Interactions with G Protein-Coupled Receptors. In: Cholesterol Regulation of Ion Channels and Receptors, Eds. I. Levitan and F.J. Barrantes. Chapter 11: 231-253. John Wiley & Sons;

  3. Abola EE, Cherezov V, and Stevens RC (2012) X-ray crystallography: crystallization. In: Comprehensive Biophysics. Eds. E.H. Egelman, H.J. Dyson. Volume 1: 34-63. Academic Press: Oxford;

  4. Liu W, Chun E, Thompson AA, Chubukov P, Xu F, Katritch V, Han GW, Roth CB, Heitman LH, IJzerman AP, Cherezov V, Stevens RC (2012) Structural basis for allosteric regulation of GPCRs by sodium ions. Science 337: 232-236; ,

    PDB ID: 4EIY

  5. Fairman JW, Dautin N, Wojtowicz D, Liu W, Noinaj N, Barnard TJ, Udho E, Przytycka TM, Cherezov V, Buchanan SK (2012) Crystal structures of the outer membrane domain of intimin and invasin from enterohemorrhagic E. coli and enteropathogenic Y. pseudotuberculosis. Structure 20: 1233-1243; ,

    PDB ID: 4E1S, PDB ID: 4E1T

  6. Chun E, Thompson AA, Liu W, Roth CB, Griffith MT, Katritch V, Kunken J, Xu F, Cherezov V, Hanson MA, Stevens RC (2012) Fusion partner toolchest for the stabilization and crystallization of G protein-coupled receptors. Structure 20: 967-976; ,

  7. Thompson AA, Liu W, Chun E, Katritch V, Wu H, Vardy E, Huang XP, Trapella C, Guerrini R, Calo G, Roth BL, Cherezov V, Stevens RC (2012) Structure of the nociceptin/orphanin FQ receptor in complex with a peptide mimetic. Nature 485: 395-399; ,

    PDB ID: 4EA3

  8. Wu H, Wacker D, Mileni M, Katritch V, Han GW, Vardy E, Liu W, Thompson AA, Huang XP, Carroll FI, Mascarella SW, Westkaemper RB, Mosier PD, Roth BL, Cherezov V, Stevens RC (2012) Structure of the human κ-opioid receptor in complex with JDTic. Nature 485: 327-332; ,

    PDB ID: 4DJH

  9. Katritch V, Cherezov V and Stevens RC (2012) Diversity and modularity of G protein-coupled receptor structures. TIPS 33: 17-27; ,

2011:

  1. Thompson AA, Liu JJ, Chun E, Wacker D, Wu H, Cherezov V, Stevens RC (2011) GPCR stabilization using the bicelle-like architecture of mixed sterol-detergent micelles. Methods 55: 310-317; ,

  2. Joseph JS, Liu W, Kunken J, Weiss TM, Tsuruta H, Cherezov V (2011) Characterization of lipid matrices for membrane protein crystallization by high-throughput small angle X-ray scattering. Methods 55: 342-349; ,

  3. Cherezov V (2011) Lipidic cubic phase technologies for membrane protein structural studies. Curr Opin Struct Biol 21: 559-566; ,

  4. Tiefenbrunn T, Liu W, Chen Y, Katritch V, Stout CD, Fee JA, Cherezov V (2011) High resolution structure of the ba3 cytochrome c oxidase from Thermus thermophilus in a lipidic environment. PLoS One 6: e22348; ,

    PDB ID: 3S8F, PDB ID: 3S8G

  5. Shimamura T, Shiroishi M, Weyand S, Tsujimoto H, Winter G, Katritch V, Abagyan R, Cherezov V, Liu W, Han GW, Kobayashi T, Stevens RC, Iwata S (2011) Structure of the human histamine H1 receptor complex with doxepin. Nature 475: 65-70; ,

    PDB ID: 3RZE

  6. Xu F, Wu H, Katritch V, Han GW, Jacobson KA, Gao ZG, Cherezov V, Stevens RC (2011) Structure of an agonist-bound human A2A adenosine receptor. Science 332: 322-327; ,

    PDB ID: 3QAK

  7. Xu F, Liu W, Hanson MA, Stevens RC, Cherezov V (2011) Development of an automated high throughput LCP-FRAP assay to guide membrane protein crystallization in lipid mesophases. Cryst Growth Des 11: 1193-1201; ,

  8. Liu W, and Cherezov V (2011) Crystallization of membrane proteins in lipidic mesophases. J Vis Exp 49: e2501; ,

2010:

  1. Chien EY, Liu W, Zhao Q, Katritch V, Han GW, Hanson MA, Shi L, Newman AH, Javitch JA, Cherezov V, Stevens RC (2010) Structure of the human dopamine D3 receptor in complex with a D2/D3 selective antagonist. Science 330: 1091-5; ,

    PDB ID: 3PBL

  2. Wu B, Chien EY, Mol CD, Fenalti G, Liu W, Katritch V, Abagyan R, Brooun A, Wells P, Bi FC, Hamel DJ, Kuhn P, Handel TM, Cherezov V, Stevens RC (2010) Structures of the CXCR4 chemokine GPCR with small-molecule and cyclic peptide antagonists. Science 330: 1066-71; ,

    PDB ID: 3ODU, PDB ID: 3OE0, PDB ID: 3OE6, PDB ID: 3OE8, PDB ID: 3OE9

  3. Cherezov V, Abola EE and Stevens RC (2010) Recent Progress in the Structure Determination of GPCRs, a Membrane Protein Family with High Potential as Pharmaceutical Targets. Methods Mol Biol 654: 141-68; ,

  4. Wacker D, Fenalti G, Brown MA, Katritch V, Abagyan R, Cherezov V, Stevens RC (2010) Conserved binding mode of human β2 adrenergic receptor inverse agonists and antagonist revealed by X-ray crystallography. J Am Chem Soc 132: 11443-5; ,

    PDB ID: 3NY8, PDB ID: 3NY9, PDB ID: 3NYA

  5. Liu W, Hanson MA, Stevens RC and Cherezov V (2010) LCP-Tm: an assay to measure and understand stability of membrane proteins in a membrane environment. Biophys J 98: 1539-48; ,

  6. Kissick DJ, Gualtieri EJ, Simpson GJ, Cherezov V (2010) Nonlinear optical imaging of integral membrane protein crystals in lipidic mesophases. Anal Chem 82: 491-7; ,

2009:

  1. Caffrey M and Cherezov V (2009) Crystallizing membrane proteins using lipidic mesophases. Nat Protoc 4: 706-731; ,

  2. Cherezov V, Hanson MA, Griffith MT, Hilgart MC, Sanishvili R, Nagarajan V, Stepanov S, Fischetti RF, Kuhn P, Stevens RC (2009) Rastering strategy for screening and centring of microcrystal samples of human membrane proteins with a sub-10 microm size X-ray synchrotron beam. J R Soc Interface 6 Suppl 5: S587-97; ,

  3. Katritch V, Reynolds KA, Cherezov V, Hanson MA, Roth CB, Yeager M, Abagyan R (2009) Analysis of full and partial agonists binding to β2-adrenergic receptor suggests a role of transmembrane helix V in agonist-specific conformational changes. J Mol Recognit 22: 307-318; ,

2008:

  1. Cherezov V, Höfer N, Szebenyi DM, Kolaj O, Wall JG, Gillilan R, Srinivasan V, Jaroniec CP, Caffrey M (2008) Insights into the mode of action of a putative zinc transporter CzrB in Thermus thermophilus. Structure 16: 1378-88; ,

    PDB ID: 3BYP, PDB ID: 3BYR

  2. Cherezov V, Liu J, Griffith M, Hanson MA, Stevens RC (2008) LCP-FRAP assay for pre-screening membrane proteins for in meso crystallization. Cryst Growth Des 8: 4307-4315; ,

  3. Cherezov V, Liu W, Derrick JP, Luan B, Aksimentiev A, Katritch V, Caffrey M. (2008) In meso crystal structure and docking simulations suggest an alternative proteoglycan binding site in the OpcA outer membrane adhesin. Proteins 71: 24-34; ,

    PDB ID: 2VDF

  4. Hanson MA, Cherezov V, Griffith MT, Roth CB, Jaakola VP, Chien EY, Velasquez J, Kuhn P, Stevens RC (2008) A specific cholesterol binding site is established by the 2.8 A structure of the human β2-adrenergic receptor. Structure 16: 897-905; ,

    PDB ID: 3D4S

  5. Jaakola VP, Griffith MT, Hanson MA, Cherezov V, Chien EY, Lane JR, Ijzerman AP, Stevens RC (2008) The 2.6 Angstrom Crystal Structure of a Human A2A Adenosine Receptor Bound to an Antagonist. Science 322: 1211-1217; ,

    PDB ID: 3EML

2007:

  1. Cherezov V and Caffrey M (2007) Membrane protein crystallization in lipidic mesophases. A mechanism study using X-ray microdiffraction. Faraday Discuss 136: 195-212; discussion 213-29; ,

  2. Cherezov V and Caffrey M (2007) Miniaturization and automation for high-throughput membrane protein crystallization in lipidic mesophases. N. E. Chayen "Protein crystallization strategies for structural genomics" San Diego: International University Line;

  3. Cherezov V, Rosenbaum DM, Hanson MA, Rasmussen SG, Thian FS, Kobilka TS, Choi HJ, Kuhn P, Weis WI, Kobilka BK, Stevens RC (2007) High-resolution crystal structure of an engineered human β2-adrenergic G protein-coupled receptor. Science 318: 1258-65; ,

    PDB ID: 2RH1

  4. Höfer N, Kolaj O, Li H, Cherezov V, Gillilan R, Wall JG, Caffrey M (2007) Crystallization and preliminary X-ray diffraction analysis of a soluble domain of the putative zinc transporter CzrB from Thermus thermophilus. Acta Crystallogr Sect F Struct Biol Cryst Commun 63: 673-7; ,

  5. Peddi A, Muthusubramaniam L, Zheng YF, Cherezov V, Misquitta Y and Caffrey M (2007) High-throughput automated system for crystallizing membrane proteins in lipidic mesophases. IEEE Trans. Autom. Sci. Eng. 4: 129-140;

  6. Rosenbaum DM, Cherezov V, Hanson MA, Rasmussen SG, Thian FS, Kobilka TS, Choi HJ, Yao XJ, Weis WI, Stevens RC, Kobilka BK (2007) GPCR engineering yields high-resolution structural insights into beta2-adrenergic receptor function. Science 318: 1266-73; ,

    PDB ID: 2RH1

2006:

  1. Cherezov V and Caffrey M (2006) Picolitre-scale crystallization of membrane proteins. Journal of Applied Crystallography 39: 604-606;

  2. Cherezov V, Clogston J, Papiz MZ, Caffrey M (2006) Room to move: crystallizing membrane proteins in swollen lipidic mesophases. J Mol Biol 357: 1605-18; ,

    PDB ID: 2FKW

  3. Cherezov V, Yamashita E, Liu W, Zhalnina M, Cramer WA, Caffrey M (2006) In meso structure of the cobalamin transporter, BtuB, at 1.95 Å resolution. J Mol Biol 364: 716-34; ,

    PDB ID: 2GUF

  4. Raman P, Cherezov V and Caffrey M (2006) The Membrane Protein Data Bank. Cell Mol Life Sci 63: 36-51; ,

  5. Shaikh SR, Cherezov V, Caffrey M, Soni SP, LoCascio D, Stillwell W, Wassall SR (2006) Molecular organization of cholesterol in unsaturated phosphatidylethanolamines: X-ray diffraction and solid state 2H NMR reveal differences with phosphatidylcholines. J Am Chem Soc 128: 5375-83; ,

  6. Siegel DP, Cherezov V, Greathouse DV, Koeppe RE 2nd, Killian JA, Caffrey M (2006) Transmembrane peptides stabilize inverted cubic phases in a biphasic length-dependent manner: implications for protein-induced membrane fusion. Biophys J 90: 200-11; ,

  7. Teeters-Kennedy SM, Rodriguez KR, Rogers TM, Zomchek KA, Williams SM, Sudnitsyn A, Carter L, Cherezov V, Caffrey M, Coe JV (2006) Controlling the passage of light through metal microchannels by nanocoatings of phospholipids. J Phys Chem B 110: 21719-27; ,

2005:

  1. Cherezov V and Caffrey M (2005) A simple and inexpensive nanoliter-volume dispenser for highly viscous materials used in membrane protein crystallization. Journal of Applied Crystallography 38: 398-400;

  2. Gordeliy VI, Cherezov V, Teixeira J (2005) Strength of thermal undulations of phospholipid membranes. Phys Rev E Stat Nonlin Soft Matter Phys 72: 061913; ,

2004:

  1. Cherezov V, Peddi A, Muthusubramaniam L, Zheng YF, Caffrey M (2004) A robotic system for crystallizing membrane and soluble proteins in lipidic mesophases. Acta Crystallogr D Biol Crystallogr 60: 1795-807; ,

  2. Misquitta LV, Misquitta Y, Cherezov V, Slattery O, Mohan JM, Hart D, Zhalnina M, Cramer WA, Caffrey M (2004) Membrane protein crystallization in lipidic mesophases with tailored bilayers. Structure 12: 2113-2124; ,

  3. Misquitta Y, Cherezov V, Havas F, Patterson S, Mohan JM, Wells AJ, Hart DJ, Caffrey M (2004) Rational design of lipid for membrane protein crystallization. J Struct Biol 148: 169-75; ,

  4. Muthusubramaniam L, Peddi A, Zheng YF, Cherezov V and Caffrey M (2004) Automating crystallization of membrane proteins by robot with soft coordinate measuring. Proc ICRA 1450-1455;

  5. Peddi A, Zheng YF, Cherezov V and Caffrey M (2004) Automating the dispensing of viscous biomaterials. Proc IROS 2: 1281-1286;

  6. Wassall SR, Brzustowicz MR, Shaikh SR, Cherezov V, Caffrey M, Stillwell W (2004) Order from disorder, corralling cholesterol with chaotic lipids. The role of polyunsaturated lipids in membrane raft formation. Chem Phys Lipids 132: 79-88; ,

  7. Wassall SR, Shaikh SR, Brzustowicz MR, Cherezov V, Siddiqui RA, Caffrey M and Stillwell W (2004) Interaction of polyunsaturated fatty acids with cholesterol: A role in lipid raft phase separation. Macromol. Symp. 219: 73-83;

2003:

  1. Cherezov V and Caffrey M (2003) Nano-volume plates with excellent optical properties for fast, inexpensive crystallization screening of membrane proteins.. J Appl Cryst 36: 1372-1377;

  2. Cherezov V, Siegel DP, Shaw W, Burgess SW, Caffrey M (2003) The kinetics of non-lamellar phase formation in DOPE-Me: relevance to biomembrane fusion. J Membr Biol 195: 165-82; ,

  3. Shaikh SR, Cherezov V, Caffrey M, Stillwell W, Wassall SR (2003) Interaction of cholesterol with a docosahexaenoic acid-containing phosphatidylethanolamine: trigger for microdomain/raft formation? Biochemistry 42: 12028-37; ,

2002:

  1. Brzustowicz MR, Cherezov V, Caffrey M, Stillwell W, Wassall SR (2002) Molecular organization of cholesterol in polyunsaturated membranes: microdomain formation. Biophys J 82: 285-98; ,

  2. Brzustowicz MR, Cherezov V, Zerouga M, Caffrey M, Stillwell W, Wassall SR (2002) Controlling membrane cholesterol content. A role for polyunsaturated (docosahexaenoate) phospholipids. Biochemistry 41: 12509-19; ,

  3. Cherezov V, Clogston J, Misquitta Y, Abdel-Gawad W, Caffrey M (2002) Membrane protein crystallization in meso: lipid type-tailoring of the cubic phase. Biophys J 83: 3393-407; ,

  4. Cherezov V, Qiu H, Pector V, Vandenbranden M, Ruysschaert JM, Caffrey M (2002) Biophysical and transfection studies of the diC(14)-amidine/DNA complex. Biophys J 82: 3105-17; ,

  5. Cherezov V, Riedl KM, Caffrey M (2002) Too hot to handle? Synchrotron X-ray damage of lipid membranes and mesophases. J Synchrotron Radiat 9: 333-41; ,

2001:

  1. Balgavy P, Kucerka N, Gordeliy VI and Cherezov VG (2001) Evaluation of small-angle neutron scattering curves of unilamellar phosphatidylcholine liposomes using a multishell model of bilayer neutron scattering length density. Acta Phys. Slovaca 51: 53-68;

  2. Cherezov V, Fersi H, Caffrey M (2001) Crystallization screens: compatibility with the lipidic cubic phase for in meso crystallization of membrane proteins. Biophys J 81: 225-42; ,

2000:

  1. Cherezov V, Cheng A, Petit JM, Diat O, Caffrey M (2000) Biophysics and synchrotron radiation where the marriage fails. X-ray damage of lipid membranes and mesophases. Cell Mol Biol (Noisy-le-grand) 46: 1133-45;

1996:

  1. Gordeliy VI, Cherezov VG, Anikin AV, Anikin MV, Chupin VV and Teixeira J (1996) Evidence of entropic contribution to hydration forces between membranes. Prog Colloid Polym Sci 100: 338-344;

  2. Gordeliy VI, Cherezov VG and Teixeira J (1996) Evidence of entropic contribution to "hydration" forces between membranes. Part II. Temperature dependence of the "hydration" force: a small angle neutron scattering study. J Mol Struct 383: 117-124;

  3. Gordeliy VI, Cherezov VG, Tugan-Baranovskaya AD and Yagujinskiy LS (1996) Investigation of the structure of thylakoid membranes (spinach) by means of small-angle neutron scattering. Biochem Mol Biol Int 38: 485-491;

  4. Klose G, Islamov A, Koenig B and Cherezov V (1996) Structure of Mixed Multilayers of Palmitoyloleoylphosphatidylcholine and Oligo(oxyethylene glycol) Monododecyl Ether Determined by X-ray and Neutron Diffraction. Langmuir 12: 409-15;

1993:

  1. Uhríková D, Cherezov V, Yaradaikin S, Balgavý P 1993) Mathematical model of the cut-off effect in the homologous series of tertiary amine local anesthetics. Pharmazie 48: 446-50;