Structures obtained by in meso crystallization (including crystallization in lipidic cubic and sponge phases).
Total structures: 62
Unique proteins: 33
GPCR Family | Total Structures | Unique Proteins | Best Resolution | |
Class A | ||||
1 | Adenosine receptors | 3 | 1 | 1.80 |
2 | Adrenergic receptors | 10 | 3 | 2.10 |
3 | Angiotensin receptors | 1 | 1 | 2.90 |
4 | Chemokine receptors | 7 | 3 | 2.50 |
5 | Dopamine receptors | 1 | 1 | 3.15 |
6 | Free fatty-acid receptors | 1 | 1 | 2.30 |
7 | Histamine receptors | 1 | 1 | 3.10 |
8 | Lysophospholipid receptors | 3 | 1 | 2.90 |
9 | Muscarinic acetylcholine receptors | 2 | 2 | 3.00 |
10 | Neurotensin receptors | 1 | 1 | 2.80 |
11 | Opioid receptors | 7 | 4 | 1.80 |
12 | Orexin receptors | 1 | 1 | 2.50 |
13 | Protease-activated receptors | 1 | 1 | 2.20 |
14 | Purinergic receptors | 5 | 2 | 2.20 |
15 | Rhodopsins | 1 | 1 | 3.20 |
16 | Serotonin receptors | 4 | 2 | 2.70 |
17 | Sphingosine 1-phosphate receptors | 2 | 1 | 2.80 |
Class B | ||||
18 | Corticotropin-releasing factor receptor | 1 | 1 | 2.98 |
19 | Glucagon receptor | 1 | 1 | 3.30 |
Class C | ||||
20 | Metabotropic glutamate receptors | 2 | 2 | 2.60 |
Class F (Frizzled) | ||||
21 | Smoothened receptor | 5 | 1 | 2.45 |
Other | ||||
22 | Viral GPCR homolog US28 | 2 | 1 | 2.89 |
CONTACT US: USC | Cherezov Lab | cherezov@usc.edu